抑郁症是血液透析患者一年内死亡的预测

Langgeng Perdhana, Shofa Chasani, S. Nuraini
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引用次数: 0

摘要

抑郁症是一种常见于血液透析患者的精神障碍。抑郁症对病人有不良影响。确定血液透析患者抑郁与全因死亡率之间关系的研究是有争议的。目的:确定抑郁症作为血液透析患者一年内全因死亡率的预测因素的作用。方法:该队列研究于2020年2月至8月在三宝垄Roemani Muhammadiyah医院血液透析室进行。纳入标准为接受血液透析≥3个月,每周两次血液透析频率,愿意参与本研究,能够良好沟通,且无既往精神障碍病史。同时,那些数据不完整、转移到另一个血液透析单位HBSAg+并有其他与血液透析或慢性肾脏疾病(CKD)无关的压力源的人被排除在本研究之外。使用Beck抑郁量表II问卷对抑郁进行评估。然后使用Kaplan-Meier和Cox回归分析收集的数据。结果:在82名受访者中,20名(24.4%)受访者被归类为抑郁症组,62名(75.6%)受访者被分类为非抑郁症组。Cox回归分析显示,抑郁症是血液透析患者一年内全因死亡率的预测因素(p值=0007,危险比=3587)。结论:抑郁是血液透析患者一年内所有死亡原因的预测因素。关键词:抑郁症、血液透析、死亡率、终末期肾病
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Depresi sebagai Prediksi Kematian dalam 1 Tahun pada Pasien Hemodialisis
Depression is a mental disorder that is often found in hemodialysis patients. Depression had bad effects on patients. The study that determines the relationship between depression and all-cause mortality risk in hemodialysis patients is debatable. Objectives: To determine the role of depression as a predictor factor of all-cause mortality within one year in hemodialysis patients. Methods: This cohort study was conducted from February to August 2020 at the hemodialysis unit of Roemani Muhammadiyah Hospital, Semarang. The inclusion criteria were undergoing hemodialysis ≥3 months, hemodialysis frequency twice a week, being willing to participate in this study, being able to communicate well, and there was no history of previous mental disorders. Meanwhile, those whose data were incomplete, transferred to another hemodialysis unit, HBSAg +, and had other stressors unrelated to hemodialysis or Chronic Kidney Disease (CKD) were excluded from this study. Depression was assessed using the Beck Depression Inventory-II questionnaire. The collected data was then analyzed using Kaplan Meier and Cox regression. Results: From 82 respondents, 20 (24,4%) respondents categorized into depression group and 62 (75,6%) respondents into non depression group. Cox Regression analysis showed that depression plays a role as a predictor factor of all-cause mortality within one year in hemodialysis patients (p value=0,007, and Hazard ratio=3,587). Conclusion: Depression plays a role as a predictor factor of all causes of mortality within one year in hemodialysis patients.Keywords: depression, hemodialysis, mortality, end-stage renal disease
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