地方病板蓝草的细胞毒性作用。来自土耳其

IF 0.9 4区生物学 Q4 PLANT SCIENCES

Israel Journal of Plant Sciences Pub Date : 2021-06-21 DOI:10.1163/22238980-bja10033

S. Kırbağ, S. Keser, S. Tekin, Ş. İnci, S. Sandal

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引用次数: 1

摘要

紫堇(Tchihatchewia isatidea Boiss)(芸苔科)在公众中被称为“红新娘”，“油漆和新娘花”。花的部分用于绘画，花枝用于治疗咳嗽。本研究研究了赤枝花部位水、乙醇和甲醇提取物对人乳腺(MCF-7)、人结肠癌(HCT-116)和人前列腺(LNCaP)癌细胞的抗癌作用。采用3-(4,5-二甲基噻唑-2-基)-2,5-二苯基溴化四唑(MTT)法检测癌细胞活力的变化。研究表明，当使用鸢尾水、乙醇和甲醇提取物时，人乳腺癌(MCF-7)、结肠癌(HCT-116)和前列腺(LNCaP)癌细胞的细胞活力有统计学意义的下降。

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Cytotoxic effect of endemic Tchihatchewia isatidea Boiss. from Turkey

Tchihatchewia isatidea Boiss (Brassicaceae) is known among the public as “Reddish Bride”, “Paint and Bridal Flower”. Flower parts are used for painting and flowering branches for treatment of cough. In this study, anticancer properties of water, ethanol and methanol extracts of Tchihatchewia isatidea flower parts were investigated against human breast (MCF-7), human colon (HCT-116) and human prostate (LNCaP) cancer cell lines. Changes in the viability of cancer cells were detected by utilizing 3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide (MTT) method. Studies have shown that there is a statistically significant decrease in the cell viability of human breast cancer (MCF-7), colon (HCT-116) and prostate (LNCaP) cancer cells when extracts of T. isatidea water, ethanol and methanol are used.

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来源期刊

Israel Journal of Plant Sciences 生物-植物科学

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Israel Journal of Plant Sciences is an international journal of extensive scope that publishes special issues dealing with all aspects of plant sciences, including but not limited to: physiology, cell biology, development, botany, genetic