茄提取物增强烧伤小鼠模型的伤口愈合和组织再生

IF 0.9 4区医学 Q4 PHARMACOLOGY & PHARMACY

Bangladesh Journal of Pharmacology Pub Date : 2019-05-21 DOI:10.3329/BJP.V14I2.40098

Zainab Qureshi, T. Khan, A. Shah, F. Wahid

{"title":"茄提取物增强烧伤小鼠模型的伤口愈合和组织再生","authors":"Zainab Qureshi, T. Khan, A. Shah, F. Wahid","doi":"10.3329/BJP.V14I2.40098","DOIUrl":null,"url":null,"abstract":"This study was conducted to evaluate the topical efficacy of Solanum incanum for the treatment of partial-thickness burn in mice model. Mice were treated with topical ointment of S. incanum three times daily for 14 days. The wound healing was observed through wound contraction and histological parameters. The group treated with S. incanum ointment showed 81% reduction in wound area as compared to negative control where wound area reduced to 22%. The histological analysis further confirmed that ointment favors the tissue regeneration and reepithelization thus heal wound rapidly as com-pared to other groups. In conclusion, S. incanum extract enhances wound healing and tissue regeneration.","PeriodicalId":8719,"journal":{"name":"Bangladesh Journal of Pharmacology","volume":" ","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2019-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/BJP.V14I2.40098","citationCount":"6","resultStr":"{\"title\":\"Solanum incanum extract enhances wound healing and tissue regeneration in burn mice model\",\"authors\":\"Zainab Qureshi, T. Khan, A. Shah, F. Wahid\",\"doi\":\"10.3329/BJP.V14I2.40098\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study was conducted to evaluate the topical efficacy of Solanum incanum for the treatment of partial-thickness burn in mice model. Mice were treated with topical ointment of S. incanum three times daily for 14 days. The wound healing was observed through wound contraction and histological parameters. The group treated with S. incanum ointment showed 81% reduction in wound area as compared to negative control where wound area reduced to 22%. The histological analysis further confirmed that ointment favors the tissue regeneration and reepithelization thus heal wound rapidly as com-pared to other groups. In conclusion, S. incanum extract enhances wound healing and tissue regeneration.\",\"PeriodicalId\":8719,\"journal\":{\"name\":\"Bangladesh Journal of Pharmacology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2019-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3329/BJP.V14I2.40098\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bangladesh Journal of Pharmacology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3329/BJP.V14I2.40098\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bangladesh Journal of Pharmacology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3329/BJP.V14I2.40098","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}

引用次数: 6

摘要

本研究旨在评价龙葵治疗小鼠部分烧伤模型的局部疗效。小鼠用S.incanum外用软膏治疗，每天3次，持续14天。通过伤口收缩和组织学参数观察伤口愈合情况。与阴性对照组相比，用S.incanum软膏治疗的组显示伤口面积减少了81%，阴性对照组的伤口面积减少到22%。组织学分析进一步证实，与其他组相比，软膏有利于组织再生和再上皮化，从而快速愈合伤口。总之，S.incanum提取物能促进伤口愈合和组织再生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Solanum incanum extract enhances wound healing and tissue regeneration in burn mice model

This study was conducted to evaluate the topical efficacy of Solanum incanum for the treatment of partial-thickness burn in mice model. Mice were treated with topical ointment of S. incanum three times daily for 14 days. The wound healing was observed through wound contraction and histological parameters. The group treated with S. incanum ointment showed 81% reduction in wound area as compared to negative control where wound area reduced to 22%. The histological analysis further confirmed that ointment favors the tissue regeneration and reepithelization thus heal wound rapidly as com-pared to other groups. In conclusion, S. incanum extract enhances wound healing and tissue regeneration.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Bangladesh Journal of Pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

1.50

自引率

18.80%

发文量

审稿时长

>12 weeks

期刊介绍： Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, peer-reviewed journal of the Bangladesh Pharmacological Society (BDPS). A scholarly publication is defined ''open access'' when there are no financial, legal or technical barriers to accessing it. Anyone can read, download, copy, distribute, print or use it in educational purpose within the legal agreements. Peer review of a manuscript means the evaluation of research work by one or more people with similar competences. It can be open or blind. We do the single-blind peer review. Our readers want to know the methodology used by the researchers which is very important to get the results. The video clip of one of the methodologies is prepared by the authors and submit it to publish.