严重急性呼吸系统综合征冠状病毒2型神经侵袭潜力：叙述性综述

Q3 Medicine

Journal of Military Medicine Pub Date : 2020-12-19 DOI:10.30491/JMM.22.11.1153

Firoozeh Alavian

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引用次数: 1

摘要

2019年12月严重急性呼吸综合征(SARS-CoV-2)的爆发导致了Covid-19的流行，最近的临床研究表明，部分神经系统、脑脊液(CSF)参与了SARS-CoV-2感染，并与头痛、头晕、嗅觉和味觉障碍等多种神经系统症状有关。本研究概述了Pubmed、谷歌Scholar和Scopus数据库;利用Covid-19、ACE2和神经系统寻找与SARS-CoV-2侵袭神经系统的临床资料相关的文章，检索了1992年至2020年的已发表文章，结果表明冠状病毒侵袭人类神经系统并引起严重的神经系统改变，因此，考虑到SARS-CoV-2特异性受体ACE2在中枢神经系统中含量丰富，鉴于其他人类冠状病毒的神经系统和侵袭性特性已被广泛报道，因此确定COVID-19可能对神经系统造成的并发症至关重要

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SARS-CoV-2 neuroinvasion potential: narrative review

The outbreak of severe acute respiratory syndrome (SARS-CoV-2) in December 2019 has led to the epidemic of Covid-19 Recent clinical studies have shown that parts of the nervous system;Cerebrospinal fluid (CSF) are involved in SARS-CoV-2 infection, which is associated with a variety of neurological manifestations such as headache, dizziness, and olfactory and gustatory disorders This study provides an overview of the Pubmed, Google Scholar and Scopus databases;and the keywords SARS-CoV-2, Covid-19, ACE2 and the nervous system were used to find articles related to the clinical data of SARS-CoV-2 invasion of the nervous system The published articles retrieved from 1992 to 2020 The findings suggest that coronaviruses invade the human nervous system and cause severe neurological changes Therefore, given that the SARS-CoV-2 specific receptor;ACE2 is abundant in the central nervous system, and the neurological and invasive properties of other human coronaviruses have been widely reported, it is essential to identify possible complications of COVID-19 on the nervous system

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来源期刊

Journal of Military Medicine Medicine-Public Health, Environmental and Occupational Health

CiteScore

2.60

自引率

0.00%

发文量

期刊介绍： Journal of Military Medicine is a Bimonthly peer-reviewed medical journal covering research and developments in the field of health and medicine in military and crisis settings. The journal was established in 1999. It publishes original research reports, editorials, letters to the editor, and reviews.