Identification of single nucleotide polymorphism within bactencin-5 and bactencin-7 coding genes in association with milk production traits

Bactencins belong to the bovine cathelicidin family of proteins, and their role in the body is significant. The study analyzed the relationship between polymorphisms within the CATHL2 and CATHL3 genes encoding the Bac-5 and Bac-7 proteins. The study included a herd of Polish Holstein-Friesian cows of the black-and-white breed. Tests were conducted using the PCR-RFLP method with the introduction of the ACRS modification. The study showed that different genetic variants within the polymorphisms studied were significantly associated with selected parameters of milk performance, such as milk yield (P ≤ 0.01), fat (P ≤ 0.01), protein (P ≤ 0.01 and P ≤ 0.05) and lactose (P ≤ 0.01 and P ≤ 0.05) content and somatic cell count (P ≤ 0.01 and P ≤ 0.05).