含辛伐他汀α-磷酸三钙微颗粒乳剂的骨诱导作用

Q4 Engineering

Nano Biomedicine Pub Date : 2017-12-30 DOI:10.11344/NANO.9.69

Akito Tateyama, Akihito Kato, H. Miyaji, Erika Nishida, Y. Iwasaki, S. Fujii, K. Kawamoto, Kanako Shitomi, Tomokazu Furihata, Kayoko Mayumi, T. Sugaya

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引用次数: 1

摘要

由于牙周病、肿瘤或囊肿导致的严重骨质流失需要进行牙槽骨重建。块状骨替代材料已在临床上用于填充较大的骨缺损[1,2];然而，它们的低成形性导致了低操作性。为了提高其可操作性，膏状骨填充剂(骨膏)有望成为骨移植材料。磷酸钙骨膏已应用于临床[3,4];而含辛伐他汀的α-磷酸三钙微颗粒乳剂对骨膏具有不可吸收性和骨诱导作用

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Bone Induction by α-tricalcium Phosphate Microparticle Emulsion Containing Simvastatin

69 Introduction Significant bone loss due to periodontal disease, tumors or cysts requires the alveolar bone reconstruction. Block-shaped bone substitute materials have been used clinically to fill large bone defects [1, 2]; however, their low shapeability leads to low operability. To improve their operability, paste-like bone filling agents (bone pastes) are anticipated to be developed as bone graft materials. Calcium phosphate bone paste has been already applied for clinical use [3, 4]; however, bone paste is non-absorbable and Bone Induction by α-tricalcium Phosphate Microparticle Emulsion Containing Simvastatin

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来源期刊

Nano Biomedicine Engineering-Biomedical Engineering

CiteScore

0.30

自引率

0.00%

发文量