番薯果皮醇提物的层析分离提高抗癌活性

Oncogen Pub Date : 2019-01-15 DOI:10.35702/onc.10002

A. Oluyori, G. Olatunji, A. Shaw, Preeti Rastogi, Meena Sanjeev, D. Dipak

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引用次数: 1

摘要

本研究采用色谱分离法对山茱萸果皮粉末乙醇提取物的正己烷部分进行分离。因此，使用硫代丹- b测定法研究了这些组分的抗癌潜力。色谱分馏得到的正己烷亚馏分具有更大的抗癌潜力。该研究强调，番薯果皮是一种富含天然抗癌分子的膳食来源，可以开发成营养保健品或作为抗癌治疗的新线索。关键词:山楂;色谱法;分离;抗癌;Sulforhodamine-B

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Chromatographic Fractionation of An Ethanolic Extract of Peels from Ipomoea batatas Lam for Improved Anticancer Activity

In this current work, the n-hexane fraction from an ethanolic extract of pulverized peel of Ipomoea batatas Lam was subjected to chromatographic fractionation. Consequently, the fractions were investigated for their anticancer potential using the Sulforhodamine-B assay. Chromatographic fractionation led to n-hexane sub-fractions with greater anticancer potential. The study highlights the peel of Ipomoea batatas Lam as a rich dietary source of natural anticancer molecules which may be developed into nutraceuticals or serve as new leads in anticancer therapy. Keywords: Ipomoea batatas; Chromatography; Fractionation; Anticancer; Sulforhodamine-B

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Oncogen

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