辉瑞- biontech公司新冠病毒疫苗诱导的脑偏瘫的临床和放射学随访

IF 2.5 Q2 CLINICAL NEUROLOGY

Tremor and Other Hyperkinetic Movements Pub Date : 2022-05-18 DOI:10.5334/tohm.688

Cédric Batot, M. Chea, S. Zeidan, M. Mongin, G. Pop, J. Mazoyer, B. Degos

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引用次数: 7

摘要

背景:偏瘫是一种罕见的多动运动障碍。病例报告:一名90岁男性在注射第二剂辉瑞- biontech COVID-19疫苗后出现左脑偏瘫。包括核磁共振成像在内的广泛调查没有发现其他原因。[18F]-氟脱氧葡萄糖-正电子发射断层扫描(FDG-PET)显示右侧壳核固定比左侧增加。患者在静脉注射皮质类固醇5天后表现出明显的改善，FDG-PET正常。讨论:本例血凝-半瘫患者在给予皮质类固醇后，壳核代谢动态恢复，反映了临床进化，提示自身免疫性COVID-19疫苗诱导的反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Clinical and Radiological Follow-Up of a Pfizer-BioNTech COVID-19 Vaccine-Induced Hemichorea-Hemiballismus

Background: Hemichorea-hemiballismus is a rare hyperkinetic movement disorder. Case Report: A 90-year-old male developed left hemichorea-hemiballismus after his second dose of the Pfizer-BioNTech COVID-19 vaccine. A wide range of investigations including magnetic resonance imaging did not reveal an alternative cause. [18F]-fluorodeoxyglucose-positron emission tomography (FDG-PET) showed increases in right putamen fixation compared to the left side. The patient showed significant improvement after five days of intravenous corticosteroids, with a normal FDG-PET. Discussion: This hemichorea-hemiballismus case shows dynamic restoration of putamen metabolism mirroring clinical evolution after administration of corticosteroids, suggesting an autoimmune COVID-19 vaccine-induced reaction.

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来源期刊

Tremor and Other Hyperkinetic Movements CLINICAL NEUROLOGY-

CiteScore

4.00

自引率

4.50%

发文量

审稿时长

6 weeks