表观遗传学与法医学:照亮未来

Q2 Pharmacology, Toxicology and Pharmaceutics
P. Astaraki, Bareza Rezaei, M. Ahadi
{"title":"表观遗传学与法医学:照亮未来","authors":"P. Astaraki, Bareza Rezaei, M. Ahadi","doi":"10.2174/1573407219666230815105041","DOIUrl":null,"url":null,"abstract":"\n\nEpigenetics deals with the changes in gene expression (no change in the genetic code) concerning certain epigenetic elements in response to the environment. Some of the most common epigenetic examples include DNA methylation, histone modifications, and non-coding RNAs. This field has been extensively applied in forensic studies, particularly to determine types of body fluids, distinguish them from mixed samples, uncovering the biological age of the forensic samples and drug-based studies. Considering recent findings, this review highlights the applications of epigenetics in forensic investigations.\n","PeriodicalId":10772,"journal":{"name":"Current Bioactive Compounds","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Epigenetics and Forensics: Brightening the Future\",\"authors\":\"P. Astaraki, Bareza Rezaei, M. Ahadi\",\"doi\":\"10.2174/1573407219666230815105041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nEpigenetics deals with the changes in gene expression (no change in the genetic code) concerning certain epigenetic elements in response to the environment. Some of the most common epigenetic examples include DNA methylation, histone modifications, and non-coding RNAs. This field has been extensively applied in forensic studies, particularly to determine types of body fluids, distinguish them from mixed samples, uncovering the biological age of the forensic samples and drug-based studies. Considering recent findings, this review highlights the applications of epigenetics in forensic investigations.\\n\",\"PeriodicalId\":10772,\"journal\":{\"name\":\"Current Bioactive Compounds\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Bioactive Compounds\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1573407219666230815105041\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Bioactive Compounds","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1573407219666230815105041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 0

摘要

表观遗传学处理的是与某些表观遗传元件有关的基因表达的变化(遗传密码没有变化)对环境的反应。一些最常见的表观遗传学例子包括DNA甲基化、组蛋白修饰和非编码RNA。该领域已被广泛应用于法医学研究,特别是确定体液类型,将其与混合样本区分开来,揭示法医样本的生物年龄和基于药物的研究。考虑到最近的发现,这篇综述强调了表观遗传学在法医学调查中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epigenetics and Forensics: Brightening the Future
Epigenetics deals with the changes in gene expression (no change in the genetic code) concerning certain epigenetic elements in response to the environment. Some of the most common epigenetic examples include DNA methylation, histone modifications, and non-coding RNAs. This field has been extensively applied in forensic studies, particularly to determine types of body fluids, distinguish them from mixed samples, uncovering the biological age of the forensic samples and drug-based studies. Considering recent findings, this review highlights the applications of epigenetics in forensic investigations.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Current Bioactive Compounds
Current Bioactive Compounds Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.90
自引率
0.00%
发文量
112
期刊介绍: The journal aims to provide comprehensive review articles on new bioactive compounds with proven activities in various biological screenings and pharmacological models with a special emphasis on stereoeselective synthesis. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia. The journal should prove to be essential reading for pharmacologists, natural product chemists and medicinal chemists who wish to be kept informed and up-to-date with the most important developments on new bioactive compounds of natural or synthetic origin, including their stereoeselective synthesis.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信