获得性累积全身神经毒性效应:医学和生物心理学的未来

R. Richardson
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引用次数: 0

摘要

由于与数十名终生反复接触毒素和溶剂的患者进行了广泛的合作,我写了一篇文章《获得性累积性神经毒性脑病:展望未来》,发表在2015年3月的《医学心理学学会通讯》上。从那以后,我回顾了数百项研究,并与其他患者合作,这些患者患有系统性疾病,如自身免疫性疾病、多种化学敏感性、过敏反应、组胺不耐受、肠道渗漏、代谢综合征和各种肌痛。他们中的许多人可以将症状的发作追溯到一个时期,在反复接触溶剂或毒素后,他们从相对正常的功能转变为严重的功能障碍。获得性累积神经毒性脑病和获得性累积全身神经毒性效应的前提是,有一个阈值,在这个阈值下,身体不能容忍额外暴露于毒素而没有显著反应。这可能与遗传敏感性、身体未能清除体内毒素和/或对身体生理/生化系统的累积损伤有关。最早为人所知的案例之一是那些演奏水晶和声的人,这是一种含铅的水晶乐器,随着时间的推移,音乐家会在他们的系统中积累铅,达到铅中毒的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acquired Cumulative Systemic Neurotoxic Effect: The Future of Medicine & Biopsychology
As a result of working extensively with dozens of patients who had repeated exposure to toxins and solvents throughout their lifetimes, I wrote the article “Acquired Cumulative Neurotoxic Encephalopathy: Look toward the Future” which was published in the Academy of Medical Psychology Newsletter in March of 2015. Since then, I have reviewed hundreds of studies, and worked with additional patients, who have the onset of systemic disorders such as autoimmune disorders, multiple chemical sensitivity, allergic reactions, histamine intolerance, leaky gut, metabolic syndrome, and various myalgia conditions. Many of them can trace the onset of symptoms back to one point where they had, after repeated exposure to solvents or toxins, gone from relatively normal function to significant dysfunction. The premise of Acquired Cumulative Neurotoxic Encephalopathy and Acquired Cumulative Systemic Neurotoxic Effect is that there is a threshold at which the body cannot tolerate additional exposure to toxins without a significant reaction. This may be related to genetic sensitivities, failure of the body to eliminate toxins from the body, and/or cumulative damage to the physiological/biochemical systems of the body. One of the first commonly known cases is those who played the crystal armonica, a leaded-crystal musical instrument, where the musician would build up lead in their system over time to the point of risks lead poisoning.
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