Trisha Mitra, S. Joardar, S. Chakravorty, Manoj Majumdar, M. Kundu, B. Roy
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Palladium-Mediated Reductive Heck Cyclization for the Synthesis of Fused Retinoid Derivatives
Linearly fused Retinoids derivatives have been synthesized via a straightforward pathway using palladium-catalyzed reductive Heck cyclization strategy. The synthesis involved a four step linear approach utilizing iodination, sulfonylation or benzylation or esterfication, palladium- catalyzed Sonogashira cross-coupling and palladium mediated reductive Heck cyclization.
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