染色质。

IF 12.1 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Annual review of biochemistry Pub Date : 2020-02-02 DOI:10.32388/s9htxi

T. Igo-Kemenes, W. Hörz, H. Zachau

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引用次数: 0

摘要

染色质亚单位核小体的大致形状现在已经知道，但其内部结构尚不清楚。最近的研究揭示了核小体内DNA组织的细节，并表明富含精氨酸的组蛋白对DNA折叠至关重要。核小体或与其相关的结构似乎存在于DNA复制和转录点；核小体内部和核小体之间的相互作用可能在这些过程中发挥关键作用。

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Chromatin.

The approximate shape of the chromatin subunit called the nucleosome is now known, but its internal architecture is not well understood. Recent studies reveal details of the organisation of DNA within the nucleosome, and show that the arginine-rich histones are essential to DNA folding. Nucleosomes or structures related to them seem to be present at points of DNA replication and transcription; interactions within and between nucleosomes are likely to play a critical part in these processes.

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来源期刊

Annual review of biochemistry 生物-生化与分子生物学

CiteScore

33.90

自引率

0.00%

发文量

期刊介绍： The Annual Review of Biochemistry, in publication since 1932, sets the standard for review articles in biological chemistry and molecular biology. Since its inception, these volumes have served as an indispensable resource for both the practicing biochemist and students of biochemistry.