Clinical Observation of Botulinum Toxin Type A Combined with Nanofat in Facial Rejuvenation Treatment

Objective: To investigate the efficacy of botulinum toxin type A combined with nanofat in the treatment of facial rejuvenation. Methods: from January 2020 to January 2021, 20 patients with facial wrinkles in our hospital (The First Affiliated Hospital of Dalian Medical University) were treated with botulinum toxin type A combined with nanofat, and the effect, duration and complications were observed. Results: After 1, 3 and 6 months of injection, the effective rates were 90%, 75% and 40%, respectively; there was no occurrence of postoperative infection, fat mass, granuloma, and other adverse reactions. Conclusion: Botulinum toxin type A combined with nanofat filling has a clear therapeutic effect in the facial rejuvenation treatment, and can improve the skin texture while improving wrinkles, which is worthy of further popularization and application in clinic.