3D打印骨骼肌组织工程支架

Pub Date : 2021-09-10 DOI:10.1142/s1793984421410075
J. Song, Xinxin Ye, Wen Chen, Li Wang, Bing Heng Lu
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引用次数: 0

摘要

骨骼肌组织工程的目的是替代或修复已经损伤或丧失部分功能的骨骼肌功能。骨骼肌组织工程是肌肉损伤修复的重要手段。以往对骨骼肌组织工程的研究主要集中在种子细胞、生物材料和生长因子等方面。近年来,这一领域的研究成果不断涌现。本文首先简要介绍了骨骼肌的解剖结构,然后结合国内外最新研究,从组织工程骨骼肌构建的基本问题到其血管化、神经化等,综述了目前利用三维(3D)打印骨骼肌组织工程的研究现状,并展望了其研究前景。
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3D Printing of Skeleton Muscle Tissue Engineering Scaffolds
The aim of skeletal muscle tissue engineering is to replace or repair skeletal muscle functions that have been injured or lost part of their functions. Skeletal muscle tissue engineering is an important strategy for muscle injury repair. The previous review on skeletal muscle tissue engineering was limited to the discussion of seed cells, biological materials and growth factors. In recent years, research results in this field have continued to emerge. This paper first briefly introduces the anatomy of skeletal muscle, and then combines the latest domestic and foreign study, from the basic problems of tissue engineering skeletal muscle construction to its vascularization, neuralization, etc., to review the current research status of skeletal muscle tissue engineering using three-dimensional (3D) printing, and look forward to its research prospects.
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