双酚A作为内分泌干扰物对人淋巴细胞的细胞毒性作用

Q4 Pharmacology, Toxicology and Pharmaceutics

Iranian Journal of Toxicology Pub Date : 2021-04-01 DOI:10.32598/IJT.15.2.753.1

M. Özgür, Ş. Yılmaz, Ash Uçar, S. Yılmaz

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引用次数: 1

摘要

方法:取健康男女各0.1 mL经肝素化的外周血0.2 mL，在无菌条件下置于培养基中。将0.027g BPA溶于1 L二甲亚砜中，制备浓度为0.05 mg/mL的对照剂量，最高剂量为50 μg/mL。分离原液后，将50 μg/mL的BPA稀释至20、10、5 μg/mL剂量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cytotoxic Effects of Bisphenol A as an Endocrine Disruptor on Human Lymphocytes

Methods: 0.1 mL heparinized 0.2 mL peripheral blood taken from a healthy male and a female were plated in culture media under sterile conditions. To prepare the reference dose at a concentration of 0.05 mg/mL, 0.027g BPA was dissolved in 1 L dimethyl sulfoxide and the highest dose of 50 μg/mL BPA solution was prepared. After separating the stock solution, 50 μg/mL BPA was diluted to prepare 20, 10 or 5 μg/mL doses.

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来源期刊

Iranian Journal of Toxicology Environmental Science-Health, Toxicology and Mutagenesis

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

9 weeks