用色谱指纹图谱和多元数据分析鉴定印尼香料中抗菌成分

IF 1.2 Q4 PHARMACOLOGY & PHARMACY

Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-02-21 DOI:10.1080/10496475.2023.2182860

Ani Afriyanti, N. D. Yuliana, Yane Regiyana, H. Kusumaningrum

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引用次数: 0

摘要

摘要本研究测定了12种姜科次要香料的抗菌活性，并采用色谱指纹图谱和多元数据分析法对最具活性的香料中的活性化合物进行了鉴定。姜黄对金黄色葡萄球菌和大肠杆菌的抗菌活性最高。采用隐式结构正交投影法，对紫苏的己烷、氯仿、乙酸乙酯、甲醇和水提取物的HPLC色谱图和抗菌数据进行了连接。保留时间为16.5–18.0 min与抗菌活性相关，在甲醇组分中大量存在。甲醇馏分的UHPLC-HRMS分析表明，该峰归因于脱甲氧基姜黄素。

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Identification of Antibacterial Components in Indonesian Minor Spices Using Chromatographic Fingerprinting and Multivariate Data Analysis

ABSTRACT This study determined the antibacterial activity of 12 minor Zingiberaceae spices and to identify the active compounds in the most active spices using chromatographic fingerprinting and multivariate data analysis. Curcuma purpurascens had the highest antibacterial activity against Staphylococcus aureus and Escherichia coli. HPLC chromatogram and antibacterial data of hexane, chloroform, ethyl acetate, methanol, and water extracts of C. purpurascens were linked using Orthogonal Projection to Latent Structure. Retention time of 16.5–18.0 min correlated with antibacterial activity and is abundantly found in methanol fraction. UHPLC-HRMS analysis of methanol fraction showed that the peak was attributed to demethoxycurcumin.

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来源期刊

Journal of Herbs, Spices and Medicinal Plants Medicine-Complementary and Alternative Medicine

CiteScore

3.00

自引率

0.00%

发文量

期刊介绍： The Journal of Herbs, Spices & Medicinal Plants is an essential reference filled with recent research and other valuable information associated with herbs, spices, and medicinal plants. The Journal serves as a focus point through which investigators and others may publish material of importance to the production, marketing, and utilization of these plants and associated extracts. The journal covers the following topics: growth, development, horticulture, ecology, physiology, genetics, chemistry, and economics. Original articles, review articles, and book reviews provide information of interest to an international audience of researchers, teachers, technicians, and managers involved with production and/or marketing of herbs, spices, and medicinal plants. Managers of food companies, food processing facilities, medical research laboratories, government agencies, and others interested in new chemicals, food additives, international trade, patents, and other items can easily review new findings. The Journal of Herbs, Spices & Medicinal Plants is a forum in which recent research and other information associated with herbs, spices, and medicinal plants is shared. The Journal represents a centralized database accessible by investigators within the international community that work with or have an interest in herbs, spices, and medicinal plants.