羊水栓塞的诊断和治疗机制及临床特点

Q4 Medicine

中华围产医学杂志 Pub Date : 2019-04-16 DOI:10.3760/CMA.J.ISSN.1007-9408.2019.04.002

A. Lin, Ye Feng, Yun Lu, Huixia Yang, Lingqun Hu

{"title":"羊水栓塞的诊断和治疗机制及临床特点","authors":"A. Lin, Ye Feng, Yun Lu, Huixia Yang, Lingqun Hu","doi":"10.3760/CMA.J.ISSN.1007-9408.2019.04.002","DOIUrl":null,"url":null,"abstract":"Amniotic fluid embolism(AFE) is a fatal intrapartum complication. Typical AFE is characterized by respiratory and circulatory failure, followed by disseminated intravascular coagulation(DIC), while atypical AFE, which had a higher survival possibility, presents with unexplained DIC only. Recent findings support an anaphylactoid inflammatory mechanism underlying the pathophysiology of AFE. Milrinone is currently the first choice for AFE due to its several functions, such as reducing pulmonary artery pressure, and improving right ventricular function through lowering heart rate and positive inotropic action. A multidisciplinary team is required in the rescue of AFE and medical staff who are skilled in critical medicine (such as anesthesiologists) often play a pivotal role. \n \n \nKey words: \nEmbolism, amniotic fluid; Mastocytosis; Hypersensitivity","PeriodicalId":52320,"journal":{"name":"中华围产医学杂志","volume":"22 1","pages":"220-222"},"PeriodicalIF":0.0000,"publicationDate":"2019-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mechanism and clinical characteristics in diagnosis and treatment of amniotic fluid embolism\",\"authors\":\"A. Lin, Ye Feng, Yun Lu, Huixia Yang, Lingqun Hu\",\"doi\":\"10.3760/CMA.J.ISSN.1007-9408.2019.04.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Amniotic fluid embolism(AFE) is a fatal intrapartum complication. Typical AFE is characterized by respiratory and circulatory failure, followed by disseminated intravascular coagulation(DIC), while atypical AFE, which had a higher survival possibility, presents with unexplained DIC only. Recent findings support an anaphylactoid inflammatory mechanism underlying the pathophysiology of AFE. Milrinone is currently the first choice for AFE due to its several functions, such as reducing pulmonary artery pressure, and improving right ventricular function through lowering heart rate and positive inotropic action. A multidisciplinary team is required in the rescue of AFE and medical staff who are skilled in critical medicine (such as anesthesiologists) often play a pivotal role. \\n \\n \\nKey words: \\nEmbolism, amniotic fluid; Mastocytosis; Hypersensitivity\",\"PeriodicalId\":52320,\"journal\":{\"name\":\"中华围产医学杂志\",\"volume\":\"22 1\",\"pages\":\"220-222\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华围产医学杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2019.04.002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华围产医学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-9408.2019.04.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

羊水栓塞(AFE)是一种致命的产时并发症。典型AFE的特征是呼吸和循环衰竭，随后出现弥散性血管内凝血(DIC)，而非典型AFE的生存可能性较高，仅表现为原因不明的DIC。最近的研究结果支持AFE的病理生理基础上的类过敏炎症机制。米力农具有降低肺动脉压、通过降低心率和正性肌力作用改善右心室功能等多种功能，是目前AFE治疗的首选药物。在AFE的抢救中需要一个多学科的团队，熟练掌握重症医学的医务人员(如麻醉师)往往发挥关键作用。关键词:栓塞;羊水;肥大细胞增多症;超敏反应

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Mechanism and clinical characteristics in diagnosis and treatment of amniotic fluid embolism

Amniotic fluid embolism(AFE) is a fatal intrapartum complication. Typical AFE is characterized by respiratory and circulatory failure, followed by disseminated intravascular coagulation(DIC), while atypical AFE, which had a higher survival possibility, presents with unexplained DIC only. Recent findings support an anaphylactoid inflammatory mechanism underlying the pathophysiology of AFE. Milrinone is currently the first choice for AFE due to its several functions, such as reducing pulmonary artery pressure, and improving right ventricular function through lowering heart rate and positive inotropic action. A multidisciplinary team is required in the rescue of AFE and medical staff who are skilled in critical medicine (such as anesthesiologists) often play a pivotal role. Key words: Embolism, amniotic fluid; Mastocytosis; Hypersensitivity

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

中华围产医学杂志 Medicine-Obstetrics and Gynecology

CiteScore

0.70

自引率

0.00%

发文量

4446

期刊介绍： Chinese Journal of Perinatal Medicine was founded in May 1998. It is one of the journals of the Chinese Medical Association, which is supervised by the China Association for Science and Technology, sponsored by the Chinese Medical Association, and hosted by Peking University First Hospital. Perinatal medicine is a new discipline jointly studied by obstetrics and neonatology. The purpose of this journal is to "prenatal and postnatal care, improve the quality of the newborn population, and ensure the safety and health of mothers and infants". It reflects the new theories, new technologies, and new progress in perinatal medicine in related disciplines such as basic, clinical and preventive medicine, genetics, and sociology. It aims to provide a window and platform for academic exchanges, information transmission, and understanding of the development trends of domestic and foreign perinatal medicine for the majority of perinatal medicine workers in my country.