OVERVIEW OF ANTIVIRAL DRUGS AGAINST SARS-CoV-2 FOR THE TREATMENT OF COVID-19

The new coronavirus SARS-CoV-2 has quickly spread all over the globe causing a global pandemic The intrinsic properties of the virus make it potentially fatal, as COVID-19 disease severity varies among individuals with currently unknown background The world community is thus in a desperate need for novel antiviral drugs against SARS-CoV-2 In this work, we focus on macromolecular targets present on SARS-CoV-2 virus as potential targets for antiviral drugs In the continuation, we offer a brief presentation of drugs or drug candidates that act directly on virus life cycle and have promising effects in COVID-19 therapy (English) [ABSTRACT FROM AUTHOR] Novi koronavirus SARS-CoV-2 brzo se prosirio svetom, uzrokujuci globalnu pandemiju Karakteristicna svojstva virusa cine ga potencijalno fatalnim, jer težina bolesti COVID-19 varira među osobama, sa trenutno nepoznatom pozadinom Svetska zajednica stoga ocajnicki traga za novim antivirusnim lekovima protiv SARS-CoV-2 virusa U ovom radu, fokusiramo se na makromolekularne ciljeve prisutne na virusu SARS-CoV-2, kao i na potencijalne ciljeve za antivirusne lekove U nastavku nudimo kratku prezentaciju lekova ili kandidata za lekove, koji deluju direktno na životni ciklus virusa i imaju obecavajuce efekte u terapiji COVID-19 bolesti (Bosnian) [ABSTRACT FROM AUTHOR] Copyright of Acta Medica Medianae is the property of Acta Medica Medianae and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )