改进牙科用骨修复材料的方法。回顾

S. Tsuperyak, I. Mochalov
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引用次数: 0

摘要

的相关性。骨移植材料广泛应用于医疗保健,特别是牙科。在口腔中使用骨成形术会增加手术区被机会性和致病性微生物群污染的风险。这些材料的一些改进有可能用于治疗牙科疾病。目的:分析目前发表的关于改进用于医疗保健和可用于牙科的骨移植材料的文献。方法。对在线数据库“PubMed”、“SciELO”、“Medcape”和“Science of Ukraine: access to knowledge”进行信息搜索时获得的数据进行分析,关键词为“osteoplasty”、“骨替代材料”、“骨缺损”。结果:尽管动物源性骨塑材料在临床应用中占主导地位,但人工材料的发展和改进前景广阔。这些方向可以是改进基于亲水凝胶的复合材料,使其能够在人体中被吸收。改性陶瓷材料和生物玻璃,改善其骨传导性能。在骨成形术中加入抗生素和防腐剂。在骨替代材料的组成中包含天然和重组生物生长因子。将骨塑材料转化为抗生素、防腐剂和生物生长因子的长期可控排放系统。结论:现代牙科骨整形材料主要是高科技医疗产品,并在不断完善。具有额外的防腐、抗菌、骨诱导和生物特性的人造材料和复合材料的创造,为改善牙科治疗和骨成形术的方法开辟了道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
WAYS FOR IMPROVEMENT THE OSTEOPLASTIC MATERIALS FOR DENTISTRY. Review
Relevance. Bone-graft materials are widely used in health care and dentistry in particular. The use of osteoplasty techniques in the oral cavity has an increased risk of contamination of the operating field with opportunistic and pathogenic microflora. A number of improvements in such materials have the potential to be used in the treatment of dental diseases. Objective: to analyze current publications devoted to the improvement of bone gratf materials that are used in health care and can be used in dentistry. Methods. An analysis of data obtained during an information search in the online databases "PubMed", "SciELO", "Medcape" and "Science of Ukraine: access to knowledge" was carried out using the keywords "osteoplasty", "bone substitute materials", " bone defects". Results: Despite the predominance in clinical practice of the use of osteoplastic materials of animal origin, the development and improvement of artificial materials looks promising. Such directions can be the improvement of composite materials based on hydrophilic gels which are able to be resorbed in the human body. Modification of ceramic materials and biological glass, improvement of their osteoconductive properties. Inclusion of antibiotics and antiseptics to osteoplastic materials. Inclusion of natural and recombinant biological growth factors in the composition of bone substitute materials. Transformation of osteoplastic material into a system of controlled long-term emission of antibiotics, antiseptics and biological growth factors. Conclusions: Modern osteoplastic materials used in dentistry are mainly high-tech medical products that continue to be improved. The creation of artificial and composite materials with additional antiseptic, antibacterial, osteoinductive and biological properties opens the way to improving the methods of dental treatment and osteoplasty for the needs of dentistry.
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