甲状腺切除术标本中甲状腺病变的患病率-城市工业区的组织形态学研究

Pub Date : 2022-01-01 DOI:10.4103/jhnps.jhnps_71_21
S. Chandanwale, Diva Sutreja, P. Patel, A. Verma, S. Kulkarni
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引用次数: 0

摘要

引言:甲状腺疾病在印度普通人群中的患病率很高,女性比男性更常见。尽管世界卫生组织的评估状况将印度列为2004年碘营养最佳的国家,但甲状腺功能减退症仍然是印度甲状腺疾病负担的主要原因。甲状腺疾病的患病率因地理区域、年龄和性别的不同而不同。本研究的目的是确定城市工业区手术切除标本中甲状腺病变的模式,并研究其组织形态学特征。材料和方法:430例甲状腺部分或全部手术切除的患者纳入研究。对其组织形态学特征进行了详细研究,并与临床表现相关联。结果:甲状腺标本以甲状腺全切除术为主,占90.71%。超过一半,即54.65%(n=235)的甲状腺切除术是在第3和第4个十年内完成的。女性患者占85.11%(n=366)。多结节性甲状腺肿是甲状腺切除术最常见的病因(n=341)。滤泡性腺瘤(n=25)和甲状腺乳头状癌(n=20)是常见的肿瘤病变。结论:与男性相比,女性甲状腺病变更需要手术干预。31-50岁是需要手术干预的最常见年龄组。16-30岁年龄段的大量年轻女性需要手术干预。碘缺乏引起的多结节性甲状腺肿似乎是甲状腺切除术最常见的原因。早期诊断和正确治疗是减少年轻女性甲状腺切除术的关键。
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Prevalence of thyroid lesions in thyroidectomy specimens - A histomorphological study in urban industrial area
Introduction: The prevalence of thyroid diseases is enormous in general population of India and more common in women than men. Although the World Health Organization assessment status has classified India as having optimal iodine nutrition in 2004, hypothyroidism still contributes significantly to burden of thyroid disorders in India. The prevalence of thyroid diseases varies according to different geographical areas, age, and sex. The aim of this study is to determine the pattern of thyroid lesions in surgically resected specimens in urban industrial area and to study their histomorphological features. Materials and Methods: The 430 patients in whom partial or complete surgical resection of thyroid was done were included in the study. The histomorphological features were studied in detail and correlated with clinical findings. Results: The majority of thyroid specimens (90.71%) were total thyroidectomies. More than half, i.e., 54.65% (n = 235) of the thyroidectomies were done in 3rd and 4th decade. The 85.11% (n = 366) were female patients. The multinodular goiter was the commonest etiology (n = 341) for thyroidectomy. The follicular adenoma (n = 25) and the papillary thyroid carcinoma (n = 20) were common neoplastic lesion. Conclusion: The thyroid lesions in females more often require surgical intervention as compared to males. The 31–50 years is the most common age group who require surgical intervention. The substantial number of younger females in the age group of 16–30 years requires surgical intervention. The multinodular goiter due to iodine deficiency appears to be most common cause of thyroidectomy. The early diagnosis and proper therapy is the key for reducing the thyroidectomies in younger females.
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