{"title":"肿瘤研究急需标准化、循证的植物免疫调节剂(如米糠阿拉伯木聚糖浓缩物/MGN-3)","authors":"T. Hajtó","doi":"10.15406/IJCAM.2017.09.00296","DOIUrl":null,"url":null,"abstract":"In the last time a case report was published that a MEK (Mitogen activated Extracellular signal regulation Kinase) inhibitors which can down regulate the receptor tyrosine kinase mediated signaling pathway [1-3] given in a combination with a standardized and evidence based plant immunomodulators was able to induce complete remissions of lung, liver and brain metastases [4]. Since these therapy modalities can’t result in similar astonishing clinical responses if they are applied separately [5] the hypothesis arouse that without standardized and evidence based plant immunomodulators the further tumor research is impeded.","PeriodicalId":92796,"journal":{"name":"International journal of complementary & alternative medicine","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Urgent Necessity for Standardized and Evidence Based Plant Immunomodulators (Such As Rice Bran Arabinoxylan Concentrate/MGN-3) for the Tumor Research\",\"authors\":\"T. Hajtó\",\"doi\":\"10.15406/IJCAM.2017.09.00296\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the last time a case report was published that a MEK (Mitogen activated Extracellular signal regulation Kinase) inhibitors which can down regulate the receptor tyrosine kinase mediated signaling pathway [1-3] given in a combination with a standardized and evidence based plant immunomodulators was able to induce complete remissions of lung, liver and brain metastases [4]. Since these therapy modalities can’t result in similar astonishing clinical responses if they are applied separately [5] the hypothesis arouse that without standardized and evidence based plant immunomodulators the further tumor research is impeded.\",\"PeriodicalId\":92796,\"journal\":{\"name\":\"International journal of complementary & alternative medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-10-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of complementary & alternative medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/IJCAM.2017.09.00296\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of complementary & alternative medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/IJCAM.2017.09.00296","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
摘要
在最近的一份病例报告中,一种MEK (Mitogen activated Extracellular signal regulation Kinase,丝分裂原活化细胞外信号调节激酶)抑制剂可以下调受体酪氨酸激酶介导的信号通路[1-3],与一种标准化的、有证据依据的植物免疫调节剂联合使用,能够诱导肺、肝和脑转移瘤[4]的完全缓解。由于这些治疗方式如果单独应用,不会产生类似的惊人的临床反应,因此假设没有标准化和基于证据的植物免疫调节剂,将阻碍进一步的肿瘤研究。
Urgent Necessity for Standardized and Evidence Based Plant Immunomodulators (Such As Rice Bran Arabinoxylan Concentrate/MGN-3) for the Tumor Research
In the last time a case report was published that a MEK (Mitogen activated Extracellular signal regulation Kinase) inhibitors which can down regulate the receptor tyrosine kinase mediated signaling pathway [1-3] given in a combination with a standardized and evidence based plant immunomodulators was able to induce complete remissions of lung, liver and brain metastases [4]. Since these therapy modalities can’t result in similar astonishing clinical responses if they are applied separately [5] the hypothesis arouse that without standardized and evidence based plant immunomodulators the further tumor research is impeded.