晕厥和QT延长与使用草药产品和m-RNA疫苗在一个年轻妇女

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL

Indian Journal of Medical Specialities Pub Date : 2023-01-01 DOI:10.4103/injms.injms_119_22

O. Pirhan, C. Yıldız

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引用次数: 0

摘要

在此，我们报告了一例31岁女性在第二剂辉瑞- biontech疫苗接种后36小时因QT延长而出现晕厥的病例。在她的综合病史记录中，她承认使用了草药制剂。她的初始心电图显示QTc间期为690 ms，她被送入重症监护病房(ICU)。她的生化检查结果显示没有电解质异常的证据，并开始口服心得安。在ICU监护期间，她出现了多形性室性心动过速，随后退化为心室颤动。遗传调查发现KCNQ1突变，并进行ICD植入。出院时给予美西汀、心得安治疗，建议门诊随访。

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Syncope and QT prolongation associated with the use of herbal product and m-RNA vaccination in a young woman

Herein, we report a case of a 31-year-old woman with syncope due to QT prolongation 36 h after the second dose of Pfizer-BioNTech vaccination. During her comprehensive history taking, she admitted the use of herbal preparation. Her initial electrocardiogram showed a QTc interval of 690 ms, and she was interned to the intensive care unit (ICU). Her biochemical findings revealed no evidence of electrolyte abnormalities, and oral propranolol was started. During ICU monitorization, she developed polymorphic ventricular tachycardia, which subsequently degenerated into ventricular fibrillation. Genetic investigation identified KCNQ1 mutation, and ICD implantation was performed. The patient was discharged with mexiletine and propranolol treatment, and the outpatient clinic follow-up was recommended.

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来源期刊

Indian Journal of Medical Specialities MEDICINE, GENERAL & INTERNAL-

自引率

16.70%

发文量

期刊介绍： The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.