Development and application of prescription review rules of rational drug use software in Xinhua Hospital Affiliated to School of Medicine，Shanghai Jiao Tong University

Objective： To introduce the development method of prescription review rules of rational drug use software in Xinhua Hospital Affiliated to School of Medicine，Shanghai Jiao Tong University.Methods： Before the launch of rational drug use software，pharmacists reviewed the prescriptions from each clinical department from August 2017 to October 2017 by software.Through comparison of the differences between software review and manual review，the prescription review rules were developed and modified.With the comprehensive application of rational drug use software from April 2018，the Pharmacy Department established the maintenance procedures for routine prescription review rules and assessment method for the performance of prescription review pharmacists，so that continuous improvement of prescription review rules could be ensured from the aspects of procedures and systems.Results： The rate of prescription rationality of the hospital increased from about 77% before the application of the rational drug use software to about 97% after its application.In addition，the application of the rational drug use software in the outpatient and inpatient promoted the compliance of off-label drug use behavior in the hospital.Conclusion： Proper placement and continuous optimization of the prescription review rules could help pharmacists to review prescriptions accurately and improve the level of rational medication in the hospital.