FLASH放射治疗对中枢神经系统和胶质瘤的影响

Q1 Health Professions

Radiation Medicine and Protection Pub Date : 2022-12-01 DOI:10.1016/j.radmp.2022.10.002

Lin Li, Yayi Yuan, Yahui Zuo

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引用次数: 0

摘要

神经胶质瘤因其潜在的高发病率、致残率和死亡率而受到广泛关注。FLASH放射治疗(FLASH- rt)因其保护正常组织的能力而成为当前研究的热门课题。本文综述了FLASH-RT在中枢神经系统和胶质母细胞瘤中的研究进展，探讨了FLASH-RT介导的中枢神经系统保护作用的潜在机制，并揭示了这项新技术在胶质瘤治疗中的优势。本研究突出了当前研究的优势和挑战，并为未来的研究提供了参考。

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A review of the impact of FLASH radiotherapy on the central nervous system and glioma

Glioma has received considerable attention because of its potential of inducing high rates of morbidity, disability, and mortality. FLASH radiotherapy (FLASH-RT) has emerged as a popular topic in current research because of its ability to protect normal tissues. The present review summarized the current development of FLASH-RT in both the central nervous system and glioblastomas, explored the potential mechanisms underlying FLASH-RT-mediated protective effects on the central nervous system, and revealed the advantages of this new technique for glioma therapy. This study highlights the benefits and challenges of the present research and provides a reference for future research.

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来源期刊

Radiation Medicine and Protection Health Professions-Emergency Medical Services

CiteScore

2.10

自引率

0.00%

发文量

审稿时长

103 days