益生菌治疗儿童抗生素相关性腹泻

Pub Date : 2023-07-01 DOI:10.1097/TIN.0000000000000332

Larissa Fadin, Karolinny Cristiny de Oliveira Vieira, Ana Clara Campagnolo Gonçalves Toledo, A. K. D. da Silva, V. C. Pereira, L. Winkelstroter

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引用次数: 0

摘要

这篇综述旨在评估益生菌在预防儿童抗生素相关性腹泻中的应用。使用PubMed、Cochrane和虚拟健康图书馆（MEDLINE/LILACS）共发现了1564项以英语发表的随机临床试验研究。一项荟萃分析包括4项鼠李糖乳杆菌亚组试验（95%置信区间[CI]:0.17-0.49；P<.00001），2项路氏乳杆菌亚群试验（95%CI:0.51-1.77；P=.87），以及5组益生菌亚组关联试验（95%CI=0.21-1.71；P=.33）。研究结果表明，单独的鼠李糖可能有助于预防儿童抗生素相关性腹泻。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Probiotics in the Management of Antibiotic-Associated Diarrhea in Children

This review aimed to evaluate probiotic use to prevent antibiotic-associated diarrhea in children. A total of 1564 studies of randomized clinical trials published in English were found using PubMed, Cochrane, and Virtual Health Library (MEDLINE/LILACS). A meta-analysis included 4 trials in subgroup Lactobacillus rhamnosus (95% confidence interval [CI]: 0.17-0.49; P < .00001), 2 trials in subgroup L reuteri (95% CI: 0.51-1.77; P = .87), and 5 groups in subgroup association of species of probiotics (95% CI: 0.21-1.71; P = .33). The findings suggest that L rhamnosus alone may be useful in preventing antibiotic-associated diarrhea in children.

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