脂联素:一个可靠的标志物

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Geetha Bhaktha, S. Nayak B, M. Shantaram
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引用次数: 0

摘要

二十年来,人们对脂联素(APN)的生物学功能已经有了很好的了解。大量的临床和动物研究为了解APN在肥胖及其相关疾病中的暴露生理功能铺平了道路。APN通过其受体介导其作用以实现其功能。APN除了对代谢有贡献外,还通过受体依赖性机制保护细胞免受细胞死亡,减少各种细胞类型的炎症,并有助于生殖功能。APN在脂肪组织和其他器官之间进行通讯,因此是肥胖及其相关发病机制的潜在治疗靶点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adiponectin: A reliable marker
The biological functioning of adiponectin (APN) has been well understood for two decades. Numerous clinical and animal studies have paved an understanding of the exposed physiological functions of APN in obesity and its related disorders. APN mediates its action through its receptors to achieve its function. Apart from its contribution to metabolism, APN also defends the cells from cell death and decreases the inflammation in various cell types through receptor-dependent mechanisms and also contributes to the reproductive function. APN communicates between adipose tissue and other organs and hence is a potential therapeutic target for obesity and its related pathogenesis.
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