脑卒中患儿临床和神经参数的动态变化及胞胆碱在治疗干预中的作用

IF 0.6 Q4 CLINICAL NEUROLOGY

Future Neurology Pub Date : 2023-01-01 DOI:10.2217/fnl-2022-0009

Shaanvar Shamuradovich Shamansurov, S. Saidazizova, N. Tulyaganova, P. Usmanova, S. O. Nazarova

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引用次数: 0

摘要

目的:由于缺乏有效的治疗方法以及药物和剂量的选择，经历中风的儿童的康复受到阻碍。我们比较了接受胞胆碱治疗的儿童的临床和神经学参数。材料与方法:我们使用儿童卒中结局测量-短期神经学检查评估了199名卒中儿童(128名男孩，64.3%)。结果:出血性梗死的诊断高于缺血性卒中，多因患儿年龄早(3个月前和3个月后)。意识障碍的存在在最急性和急性期是值得注意的。结论:小儿脑卒中预后测量-短神经学检查量表可用于预测不良预后。胞胆碱可以早期使用，在生命的第一年尤其有效。

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Dynamics of clinical and neurological parameters and role of citicoline during therapeutic interventions in children with stroke

Aim: The rehabilitation of children who experience stroke is hampered by the lack of proven treatments and the choice of drugs and dosages. We compared clinical and neurological parameters in children receiving citicoline. Materials & methods: We assessed 199 children (128 boys, 64.3%) with stroke using the Pediatric Stroke Outcome Measure–Short Neurological Exam. Results: Hemorrhagic infarction was diagnosed more often than ischemic stroke, most often owing to the child’s early age (before and after 3 months). The presence of disorders of consciousness in the most acute and acute periods is noteworthy. Conclusion: The Pediatric Stroke Outcome Measure–Short Neurological Exam scale can be used to predict adverse outcomes. Citicoline can be administered early and is especially effective during the first year of life.

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来源期刊

Future Neurology CLINICAL NEUROLOGY-

CiteScore

2.10

自引率

0.00%

发文量

期刊介绍： The neurological landscape is changing rapidly. From the technological perspective, advanced molecular approaches and imaging modalities have greatly increased our understanding of neurological disease, with enhanced prospects for effective treatments in common but very serious disorders such as stroke, epilepsy, multiple sclerosis and Parkinson’s disease. Nevertheless, at the same time, the healthcare community is increasingly challenged by the rise in neurodegenerative diseases consequent upon demographic changes in developed countries.