L. Ploux, Min Jin, Sophie Hellé, Cosette Betscha, J. Strub, M. Metz-Boutigue
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引用次数: 0
摘要
Land D-Cateslytin（CTL）是一种来源于嗜铬粒蛋白A的抗微生物肽（AMP），嗜铬粒素A是一种应激反应系统的蛋白质。它们的抗微生物性能已经得到了充分的表征，并已在生物材料中得到开发。然而，对酵母和细菌生物膜的影响从未得到具体的解决。我们研究了CTL的L和D构型对白色念珠菌、大肠杆菌或金黄色葡萄球菌微生物形成的生物膜生长的影响。
The versatile effect of L- and D-Cateslytin on bacteria and yeast biofilms according to configuration, medium and dose
Land D-Cateslytin (CTL) are antimicrobial peptides (AMP) derived from chromogranin A, a protein of the stress response system. Their antimicrobial properties have been thoroughly characterized and already exploited in biomaterials. However, effects on biofilms of yeast and bacteria have never been specifically addressed. We have investigated the impact of both L and D configurations of CTL on the growth of biofilms formed by Candida albicans, Escherichia coli or Staphylococcus aureus microorganisms.
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