超声弹性成像在甲状腺结节评估中的应用及其与细胞学的相关性

IF 0.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Vikrant Kanagaraju, S. Sukithra, N. Jayaprakash, B. Devan
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引用次数: 0

摘要

背景:超声弹性成像(USE)已成为评估甲状腺结节的潜在有用工具。本研究的目的是以细针穿刺细胞学(FNAC)分析为参考标准,评估弹性成像在区分甲状腺良恶性结节方面的疗效。材料和方法:这是一项2014年5月至2015年3月在南印度一家三级护理中心进行的横断面前瞻性研究。连续接受常规超声检查的甲状腺实性结节患者接受了USE检查,然后在超声引导下对甲状腺结节进行FNAC检查。B超和USE检查结果与细胞学检查结果相关。使用SPSS版本24进行统计分析。描述性统计以平均值±标准差表示。计算USE的诊断敏感性、特异性、阳性预测值和阴性预测值。结果:共有60名患有60个甲状腺实性结节的患者被纳入研究。患者的平均年龄为48.27±16.10岁。女性占83.3%。细胞病理学分析中良性结节的发生率为60%(n=36)。超声检查发现75%的恶性病变边界不规则或边界不清,边缘有小叶。以FNAC为参考标准,USE的敏感性、特异性、阳性预测值和阴性预测值分别为91.7%、77.77%、73.33%和93.3%。结论:弹性成像具有较高的诊断准确性和与恶性细胞学的相关性,是区分甲状腺良恶性结节的一种有效的非侵入性辅助工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utility of ultrasound elastography in evaluation of thyroid nodules and correlation with cytology
Background: Ultrasound elastography (USE) has emerged as a potentially useful tool in the evaluation of thyroid nodules. The aim of this study was to assess the efficacy of elastography in differentiating benign from malignant thyroid nodules with fine-needle aspiration cytology (FNAC) analysis as reference standard. Materials and Methods: This was a cross-sectional prospective study carried out at a tertiary care center in South India between May 2014 and March 2015. Consecutive patients with solid nodule in the thyroid gland on conventional ultrasound (US) underwent USE, followed by US-guided FNAC of the thyroid nodule. The findings of B-mode images and USE were correlated with cytology. Statistical analysis was performed using SPSS version 24. Descriptive statistics were presented as mean ± standard deviation. The diagnostic sensitivity, specificity, positive predictive value, and negative predictive value of USE were calculated. Results: A total of sixty patients with sixty solid thyroid nodules were enrolled in the study. The mean age of the patients was 48.27 ± 16.10 years. About 83.3% were females. The frequency of benign nodules on cytopathologic analysis was 60% (n = 36). Seventy-five percent of the malignant lesions had irregular or poorly defined borders with lobulated margins on US. The sensitivity, specificity, positive predictive value, and negative predictive value of USE were 91.7%, 77.77%, 73.33%, and 93.3%, respectively, with FNAC as reference standard. Higher elastography scores were found to be significantly associated with malignant cytology (P = 0.0001). Conclusion: Elastography, with its fairly high diagnostic accuracy and correlation with malignant cytology, can be an effective noninvasive adjunctive tool in distinguishing benign from malignant thyroid nodules.
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来源期刊
West African Journal of Radiology
West African Journal of Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
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