通过3D打印进行药物递送和测试

Q1 Computer Science
Virender Kumar , Harmanpreet Kaur , Anuradha Kumari , Goldy Hooda , Vandana Garg , Harish Dureja
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引用次数: 2

摘要

3D打印最早出现在1984年。从那时起,它在包括制药工业在内的各个领域得到了广泛的应用。3D打印是通过一层一层地沉积材料来制造产品的过程。因此,也称为增材制造。增材制造提供了患者特定配方,这是传统药物设计方法的优势。3D打印有助于复杂结构的设计。自从第一台3d打印平板电脑获得批准以来,这一领域已经得到了普及。在这篇综述中,讨论了3D打印中使用的各种技术。本文进一步深入了解了最近对增材制造技术的研究。关于使用AM技术为儿科患者制作的配方也有一些讨论。在这项工作中提到的不同类型的药物输送系统有口服、阴道、直肠、口腔粘膜、透皮和植入。进一步的药物测试设备,包括3d打印类器官和器官芯片模型,已经被讨论。最后,给出了该技术的未来发展方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Drug delivery and testing via 3D printing

3D printing first came into existence in the year 1984. Since then, it has found significant use in various fields, including pharmaceutical industries.3D printing is a process of manufacturing products by depositing materials layer by layer. Thus, also called additive manufacturing. Additive manufacturing provides patient-specific formulation, an advantage over conventional drug design methods. 3D printing helps in the designing of complex structures. Since the approval of the first 3D-printed tablet, this field has gained popularity. In this review, various techniques used in 3D printing have been discussed. This article further gives insight into the recent research done on AM technology. There is also some discussion about the formulations made for pediatric patients using AM technology. Different types of drug delivery systems mentioned in this work are oral, vaginal, rectal, oro-mucosal, transdermal, and implant. Further drug testing devices, including 3D-printed organoids and organ-on-chip models, have been discussed. Finally, it gives information about the future direction of this technology.

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来源期刊
Bioprinting
Bioprinting Computer Science-Computer Science Applications
CiteScore
11.50
自引率
0.00%
发文量
72
审稿时长
68 days
期刊介绍: Bioprinting is a broad-spectrum, multidisciplinary journal that covers all aspects of 3D fabrication technology involving biological tissues, organs and cells for medical and biotechnology applications. Topics covered include nanomaterials, biomaterials, scaffolds, 3D printing technology, imaging and CAD/CAM software and hardware, post-printing bioreactor maturation, cell and biological factor patterning, biofabrication, tissue engineering and other applications of 3D bioprinting technology. Bioprinting publishes research reports describing novel results with high clinical significance in all areas of 3D bioprinting research. Bioprinting issues contain a wide variety of review and analysis articles covering topics relevant to 3D bioprinting ranging from basic biological, material and technical advances to pre-clinical and clinical applications of 3D bioprinting.
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