The Potential Role of Exercise on the Bioavailability of Cancer Treatments

Recently, exercise in oncology has been proposed as an effective strategy in managing symptoms, reducing psychological distress (i.e. anxiety, depression) and easing the harmful effects of treatments. The studies showing the direct benefits of exercise on cancer are valuable. However, the mechanisms leading to these improvements are still unclear. The practice of exercise may influence the pharmacokinetics of drugs, but the number of studies in this field is limited. It then seems legitimate to hypothesize that exercise plays a role in the bioavailability of cancer drugs. As a matter of fact, no articles have focused on the role of exercise in the bioavailability of cancer drugs. This article shows a poverty of data examining the role of exercise in the bioavailability of cancer drugs. To our knowledge, this is the first published article to examine this issue.