羊奶开菲尔作为抗高血糖食物的临床前研究

IF 1.3 Q4 FOOD SCIENCE & TECHNOLOGY
S. Susanti, N. Nurwantoro, Jessen Juan Elto, Trilaksana Nugroho, A. Suryani, H. Rizqiati
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引用次数: 1

摘要

背景:山羊奶开菲尔是一种功能性食品,具有许多健康益处,包括控制血糖、降低胆固醇和改善消化健康。本研究旨在确定食用开菲尔对高血糖小鼠(Mus musculus)血糖水平的影响,而不影响其他血液化学成分。这项研究将山羊奶开菲尔产品与其他被认为能够控制和降低血糖水平的加工奶产品进行了比较。目的:本研究旨在将山羊奶开菲尔产品与其他被认为能够控制和降低血糖水平的加工食品进行比较。方法:以21只小鼠为实验动物,采用高脂肪、高果糖饮食诱导21天血糖升高。诱导后,根据治疗方法将小鼠分为3组,即口服额外的蒸馏水(安慰剂)、迪亚贝他索®(阳性对照)和羊奶开菲尔,每组9人。结果:治疗对血糖及β-酮水平有显著影响。补充Diabetasol®和山羊kefir的小鼠血糖水平低于对照组(p<0.05),补充山羊ke菲尔的小鼠血液β-酮水平低于对照和Diabetasor®(p<0.05)。同时,红细胞比容和血红蛋白水平在治疗之间没有显着差异。结论:研究结果表明,山羊奶开菲尔作为一种抗高血糖功能性食品具有临床前潜力,不会影响其他血液化学特征。关键词:抗高血糖,血糖,山羊克菲尔
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preclinical study of goat milk kefir as an antihyperglycemic food
Background: Goat milk kefir is a functional food with numerous health benefits, including blood sugar control, cholesterol reduction, and improved digestive health. This study aims to determine the effect of kefir consumption on blood glucose levels in hyperglycaemic mice (Mus musculus) without affecting another blood chemistry.  This study compared goat milk kefir products to other processed milk products considered to be capable of controlling and reducing blood sugar levels. Objective:This study aimed to compare goat milk kefir products to other processed food products considered to be capable of controlling and reducing blood sugar levels.Methods: Twenty-one mice, as experimental animals, were induced for 21 days with the high-fat and high fructose diet to increase blood sugar levels. After induction, mice were divided into 3 groups according to treatment, namely oral administration of additional distilled water (placebo), diabetasol® (positive control), and goat's milk kefir with each group consisting of 9 individuals. Results: Treatment showed significant effect on the blood glucose and β-ketone level. Diabetasol®  and Goat kefir supplemented mice had a lower blood glucose level than control (p < 0.05) and goat kefir supplemented mice had lower blood β-ketone level than control and Diabetasol® (p< 0.05). Meanwhile, hematocrit and hemoglobin levels did not show significant differences between treatments.Conclusion: The results suggested that goat milk kefir has preclinical potential as an antihyperglycemic functional food without affecting other blood chemistry profiles.Keywords: Antihyperglycemic, blood sugar, goat kefir
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来源期刊
Functional Foods in Health and Disease
Functional Foods in Health and Disease FOOD SCIENCE & TECHNOLOGY-
CiteScore
2.20
自引率
20.00%
发文量
47
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