一名患有局灶性脑炎的12岁菲律宾男孩的严重急性呼吸系统综合征冠状病毒2型嗜神经性

Q4 Medicine
Anna Dominique Py Castro, M. A. A. Valencia, Jay Ron Padua
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引用次数: 1

摘要

冠状病毒(新冠肺炎)大流行,有报告称新冠肺炎的神经系统表现,主要发生在成人中,但也有少数病例发生在儿童中。已经提出了几种机制来解释严重急性呼吸综合征冠状病毒2(SARS-CoV-2)如何导致神经系统损伤。新冠肺炎出现了支持性神经变性和神经侵袭,脑脊液聚合酶链式反应(PCR)阳性结果为13%,儿科讨论了一例局灶性脑炎病例,该病例在与新冠肺炎相关的发烧和轻度呼吸道疾病后出现癫痫发作和精神状态改变。该病例的一个显著方面是在CSF中检测到严重急性呼吸系统综合征冠状病毒2型核糖核酸,尽管在两个连续的鼻咽拭子标本中没有检测到。已从
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SARS-CoV-2 Neurotropism in a 12-Year-Old Filipino Boy with Focal Encephalitis
coronavirus (COVID-19) pandemic, there been reports of neurological manifestations of COVID-19, mostly in adults, albeit with a few cases described in children Several mechanisms have been proposed to explain how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may in-duce neurological damage. There is emerging supporting neurotropism and neuroinvasion in COVID-19, with polymerase chain reaction (PCR) of the cerebrospinal fluid positive results 13% of and pediatric of the discusses a case of focal encephalitis presenting with seizure and altered mental status following fever and mild respiratory illness associated with COVID-19. A notable aspect of this case was the detection of SARS-CoV-2 RNA in the CSF, despite its absence in two consecu-tive nasopharyngeal swab specimens. Written in-formed consent for publication was obtained from the
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来源期刊
Annals of Child Neurology
Annals of Child Neurology Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.50
自引率
0.00%
发文量
35
审稿时长
8 weeks
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