二甲双胍相关性乳酸中毒1例报告

IF 0.1 Q4 EMERGENCY MEDICINE
I. Akbas, Caner Akufuk, Muhammet Mustafa Yilmaz, Atilla Eren Kurt, Fatih Coşkun
{"title":"二甲双胍相关性乳酸中毒1例报告","authors":"I. Akbas, Caner Akufuk, Muhammet Mustafa Yilmaz, Atilla Eren Kurt, Fatih Coşkun","doi":"10.33706/jemcr.1294738","DOIUrl":null,"url":null,"abstract":"Metformin is an oral antidiabetic drug of the biguanide classused in type 2 diabetic patients with normal renal function. The mortality rate is high in cases of lactic acidos is developing in metformin intoxication. In the emergency department, metformin intoxication should be considered in the differential diagnosis of patients whouse metformin and have high anion gap metabolic acidosis (lactic acidosis). The most important and effective treatment with early diagnosis is correction of metabolic acidosis with hemodialysis or hemofiltration methods, bicarbonate treatment, adjustment of blood glucose level. Cardiovascular system support therapy significantly reduces morbidity/mortality. In this case report, we present the early diagnosis and successful treatment of a patient with lactic acidosis due to metformin intoxication.","PeriodicalId":41189,"journal":{"name":"Journal of Emergency Medicine Case Reports","volume":" ","pages":""},"PeriodicalIF":0.1000,"publicationDate":"2023-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A Case Report of Metformin Related Lactic Acidosis\",\"authors\":\"I. Akbas, Caner Akufuk, Muhammet Mustafa Yilmaz, Atilla Eren Kurt, Fatih Coşkun\",\"doi\":\"10.33706/jemcr.1294738\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Metformin is an oral antidiabetic drug of the biguanide classused in type 2 diabetic patients with normal renal function. The mortality rate is high in cases of lactic acidos is developing in metformin intoxication. In the emergency department, metformin intoxication should be considered in the differential diagnosis of patients whouse metformin and have high anion gap metabolic acidosis (lactic acidosis). The most important and effective treatment with early diagnosis is correction of metabolic acidosis with hemodialysis or hemofiltration methods, bicarbonate treatment, adjustment of blood glucose level. Cardiovascular system support therapy significantly reduces morbidity/mortality. In this case report, we present the early diagnosis and successful treatment of a patient with lactic acidosis due to metformin intoxication.\",\"PeriodicalId\":41189,\"journal\":{\"name\":\"Journal of Emergency Medicine Case Reports\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.1000,\"publicationDate\":\"2023-05-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Emergency Medicine Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33706/jemcr.1294738\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"EMERGENCY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Emergency Medicine Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33706/jemcr.1294738","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"EMERGENCY MEDICINE","Score":null,"Total":0}
引用次数: 1

摘要

二甲双胍是一种双胍类口服抗糖尿病药物,用于肾功能正常的2型糖尿病患者。二甲双胍中毒并发乳酸的病例死亡率较高。在急诊科,在鉴别诊断使用二甲双胍并患有高阴离子间隙代谢性酸中毒(乳酸酸中毒)的患者时,应考虑二甲双胍中毒。早期诊断的最重要和有效的治疗方法是用血液透析或血液过滤方法纠正代谢性酸中毒,碳酸氢盐治疗,调整血糖水平。心血管系统支持治疗显著降低发病率/死亡率。在本病例报告中,我们介绍了一例因二甲双胍中毒引起的乳酸酸中毒患者的早期诊断和成功治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Report of Metformin Related Lactic Acidosis
Metformin is an oral antidiabetic drug of the biguanide classused in type 2 diabetic patients with normal renal function. The mortality rate is high in cases of lactic acidos is developing in metformin intoxication. In the emergency department, metformin intoxication should be considered in the differential diagnosis of patients whouse metformin and have high anion gap metabolic acidosis (lactic acidosis). The most important and effective treatment with early diagnosis is correction of metabolic acidosis with hemodialysis or hemofiltration methods, bicarbonate treatment, adjustment of blood glucose level. Cardiovascular system support therapy significantly reduces morbidity/mortality. In this case report, we present the early diagnosis and successful treatment of a patient with lactic acidosis due to metformin intoxication.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
22
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信