M. Rabiei, A. Zali, Sara Rahmati Roodsari, Zahra Arab-Mazar, E. Lotfali
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Fungal Central Nervous System Infections in Patients With COVID-19
Recent studies have indicated that fungal co-infections have a major impact on the morbidity and mortality of patients with COVID-19. In these patients, the excessive production of inflammatory cytokines and the reduction in CD4 + T and CD8 + T cell count entails susceptibility to fungal infections.1 In addition to impaired cell-mediated immunity, comorbidities and immunosuppressive medications have a significant role in the development of fungal infections and have serious impacts on clinical outcomes.1-3.
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