壳聚糖- 5,7-二(1-羟基-1-三氟甲基-2,2,2-三氟乙基)-8-羟基喹啉生物复合材料的制备及性能研究

IF 1.1 4区化学 Q4 CHEMISTRY, PHYSICAL

Doklady Physical Chemistry Pub Date : 2022-03-12 DOI:10.1134/S0012501621110014

I. S. Chaschin, E. I. Perepelkin, V. I. Dyachenko

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引用次数: 1

摘要

将5,7-二(1-羟基-1-三氟甲基-2,2,2-三氟乙基)-8-羟基喹啉(FOQ)在60%乙酸中浸渍于壳聚糖中，得到了一种新的生物有机复合材料。由于壳聚糖的氨基和FOQ的高酸性OH基团之间的氢键，所得到的配合物具有很高的稳定性。该复合材料抑制革兰氏阳性和革兰氏阴性细菌生长的程度比原始壳聚糖大得多。该生物复合材料有望作为延长心脏假体中胶原基质使用寿命的抗菌涂层。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Preparation and Study of Properties of a New Biocomposite of Chitosan with 5,7-Bis(1-hydroxy-1-trifluoromethyl-2,2,2-trifluoroethyl)-8-hydroxyquinoline

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Preparation and Study of Properties of a New Biocomposite of Chitosan with 5,7-Bis(1-hydroxy-1-trifluoromethyl-2,2,2-trifluoroethyl)-8-hydroxyquinoline

A new bioorganic composite was obtained by impregnation of 5,7-bis(1-hydroxy-1-trifluoromethyl-2,2,2-trifluoroethyl)-8-hydroxyquinoline (FOQ) into chitosan in 60% acetic acid. The resulting complex was found to be highly stable due to hydrogen bonding between the amino groups of chitosan and the highly acidic OH groups of FOQ. This composite inhibited the growth of gram-positive and gram-negative bacteria to a much greater extent than pristine chitosan. It is expected that the biocomposite would be used as an antibacterial coating with a prolonged service life for collagen matrices used for cardiac prostheses.

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来源期刊

Doklady Physical Chemistry 化学-物理化学

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Doklady Physical Chemistry is a monthly journal containing English translations of current Russian research in physical chemistry from the Physical Chemistry sections of the Doklady Akademii Nauk (Proceedings of the Russian Academy of Sciences). The journal publishes the most significant new research in physical chemistry being done in Russia, thus ensuring its scientific priority. Doklady Physical Chemistry presents short preliminary accounts of the application of the state-of-the-art physical chemistry ideas and methods to the study of organic and inorganic compounds and macromolecules; polymeric, inorganic and composite materials as well as corresponding processes. The journal is intended for scientists in all fields of chemistry and in interdisciplinary sciences.