Half-Sandwich d 6 -Metal (Co III , Rh III , Ir III , Ru II )-Catalyzed Enantioselective C–H Activation

Transition metal-catalyzed enantioselective C–H activation has provided a straightforward strategy to synthesize chiral molecules from readily available sources. In this graphic review, we summarized the progress of half-sandwich d6 metal (CoIII, RhIII, IrIII, RuII) catalyzed enantioselective C–H functionalization reactions. The review was categorized according to the types of metal catalysts and chiral ligands. Representative enantio-determining models and catalytic cycles were presented. We hope this graphic review would stimulate further efforts on the development of novel chiral ligands and strategies in this emerging research topic.