一例SARS-COV-2阳性患者由劳伦隐球菌引起的非新生肺隐球菌病

Priscilla Duran Luciano
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引用次数: 1

摘要

非新生隐球菌以前被认为是腐生植物,对人类无致病性[1-2]。然而,在过去的几十年里,免疫功能低下和免疫功能正常的患者中劳伦隐球菌感染的发病率逐渐增加[1-2]。在COVID-19大流行期间,在严重的SARS-CoV-2感染患者中报告了多例机会性细菌和真菌感染病例。作者报告了一例接受托珠单抗和地塞米松治疗的重症COVID-19患者中由劳伦隐球菌引起的机会性肺隐球菌病。该病例有助于扩大对SARS-COV-2感染后出现的继发性感染并发症(包括机会性病原体)的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-Neoformans Pulmonary Cryptococcosis Due to Cryptococcus Laurentii in a Positive SARS-COV-2 Patient
Non-neoformans Cryptococcus species were formerly considered to be saprophytes and nonpathogenic to humans [1-2]. However, the incidence of Cryptococcus laurentii infections in immunocompromised and immunocompetent patients has been gradually increasing over the last decades [1-2]. During the COVID-19 pandemic, multiple cases of opportunistic bacterial and fungal infections have been reported in patients after a severe SARS-CoV-2 infection. The author reports the first case of opportunistic pulmonary cryptococcosis caused by Cryptococcus laurentii in a severely ill COVID-19 patient who received treatment with Tocilizumab and dexamethasone. This case contributes to the expanding knowledge of emergent secondary infectious complications including opportunistic pathogens after a SARS-COV-2 infection.
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