白头翁不同提取物对伤口愈合的影响

IF 0.9 4区医学 Q4 PHARMACOLOGY & PHARMACY

Bangladesh Journal of Pharmacology Pub Date : 2019-01-14 DOI:10.3329/BJP.V14I1.38444

Barış Ötün, U. Yücel

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引用次数: 5

摘要

在本研究中，评估了不同的白头翁提取物对大鼠背部穿孔活检造成的6mm伤口的影响。将植物的叶子粉末化，用蒸馏水、甲醇、正己烷和乙酸乙酯提取。提取液以凡士林油的形式获得，并局部应用于伤口。在第0、2、4、6、8、10和12天进行伤口测量，并在第12天进行组织病理学检查。正己烷提取物对伤口愈合具有加速作用，并对愈合过程做出了积极贡献。总之，翼龙的伤口愈合特性在新药开发研究中具有广阔的前景。

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Wound healing effect of different extracts of Centaurea pterocaula

In this study, the effect of different extracts of Centaurea pterocaula were evaluated on 6 mm wound created by punch biopsy on the rat back. The leaves of the plant were powdered and extracted with distilled water, methanol, n-hexane and ethyl acetate. Extracts were obtained in the form of pomade with vaseline and applied topically to the wounds. The wound measurements performed on day 0, 2, 4, 6, 8, 10 and 12 and the histo-pathological examination performed on day 12. The n-hexane extract had an accelerating effect on wound healing and made a positive contribution to the healing process. In conclusion, C. pterocaula has a promising future for new drug development studies by its wound healing property.

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来源期刊

Bangladesh Journal of Pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

1.50

自引率

18.80%

发文量

审稿时长

>12 weeks

期刊介绍： Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, peer-reviewed journal of the Bangladesh Pharmacological Society (BDPS). A scholarly publication is defined ''open access'' when there are no financial, legal or technical barriers to accessing it. Anyone can read, download, copy, distribute, print or use it in educational purpose within the legal agreements. Peer review of a manuscript means the evaluation of research work by one or more people with similar competences. It can be open or blind. We do the single-blind peer review. Our readers want to know the methodology used by the researchers which is very important to get the results. The video clip of one of the methodologies is prepared by the authors and submit it to publish.