GIANT NODULAR BASAL CELL SKIN CANCER

Clinical observations of primary giant nodular basal cell skin cancer in two patients with a gender ratio of 1:1 at the age of 64 and 68 years and disease duration of 20 and 15 years, respectively, are presented. The reasons for the late appeal of patients for medical help are established - psychological states of fear and anxiety. The clinical picture of the presented observations was characterized by a slow long-term asymptomatic growth of solitary tumor-like nodes of a mushroom-shaped form of stagnant pink color with a bumpy surface, densely elastic consistency, soldered to the underlying soft tissues, sizes 9.5x7.0 cm and 5.0x9.0 cm, respectively. Giant basaliomas were localized on the scalp in a woman and on the skin of the trunk in a man. The clinical features of the tumors corresponded to those of a large conglomerated basal cell skin cancer. A description of the clinical and dermatoscopic picture of giant nodular basaliomas is presented. The patients underwent radical surgical excision of tumors with pathomorphological examination of the postoperative material. The histological picture of giant basal cell carcinoma in both cases is represented by tumors of a complex structure - a solid adenoid type with invasion into the reticular dermis and subcutaneous fat. The low biological potential of giant nodular basaliomas has been established.