射波刀机器人放射外科和Radixact系统用于肺癌和前列腺癌立体定向放射治疗的Synchrony®实时运动跟踪治疗方案的剂量学比较

IF 0.3 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Radiotherapy in Practice Pub Date : 2022-04-21 DOI:10.1017/S1460396922000061

C. Kong, T. Chiu, H. Geng, W. Lam, B. Yang, C. Cheung, S. Yu

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引用次数: 0

摘要

本研究的目的是评估Radixact或CyberKnife哪台机器在使用Synchrony®实时运动跟踪系统进行肺和前列腺立体定向放射治疗(SBRT)时效果更好。选择10例和8例分别使用射波刀系统进行肺和前列腺SBRT治疗的患者进行评估。对于每位患者，回顾性Radixact计划被创建，并与原始射波刀计划进行比较。Radixact方案与射波刀方案在肺、前列腺SBRT中的新符合性指数差异无统计学意义。Radixact方案肺和前列腺SBRT的平均均匀性指数均较好，差异均有统计学意义(肺p = 0.04，前列腺p = 0.02)。在肺部SBRT中，射波刀方案对肺部的剂量较低(p = 0.002)。在前列腺SBRT中，射波刀计划和Radixact计划在保留危险器官方面无统计学差异。综上所述，射波刀治疗肺部SBRT效果较好，而Radixact治疗前列腺SBRT效果较好。

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Dosimetric comparison of Synchrony® real-time motion tracking treatment plans between CyberKnife robotic radiosurgery and Radixact system for stereotactic body radiation therapy of lung and prostate cancer

Abstract The aim of this study was to assess which machine, Radixact or CyberKnife, can deliver better treatment for lung and prostate stereotactic body radiation therapy (SBRT) with the use of Synchrony® real-time motion tracking system. Ten and eight patients treated with lung and prostate SBRT, respectively, using the CyberKnife system were selected for the assessment. For each patient, a retrospective Radixact plan was created and compared with the original CyberKnife plan. There was no statistically significant difference in the new conformity index of the Radixact plans and that of the Cyberknife plans in both lung and prostate SBRT. The average homogeneity index in the Radixact plans was better in both lung and prostate SBRT with statistical significance (p = 0·04 for lung and p = 0·02 for prostate). In lung SBRT, the dose to lungs was lower in Cyberknife plans (p = 0·002). In prostate SBRT, there was no statistically significant difference in organs at risk sparing between Cyberknife plans and Radixact plans. In conclusion, CyberKnife was better in lung SBRT while Radixact was better in prostate SBRT.

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来源期刊

Journal of Radiotherapy in Practice RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： Journal of Radiotherapy in Practice is a peer-reviewed journal covering all of the current modalities specific to clinical oncology and radiotherapy. The journal aims to publish research from a wide range of styles and encourage debate and the exchange of information and opinion from within the field of radiotherapy practice and clinical oncology. The journal also aims to encourage technical evaluations and case studies as well as equipment reviews that will be of interest to an international radiotherapy audience.