一例老年妇女药物诱导的显微镜下结肠炎

IF 0.4 Q4 GERONTOLOGY

Journal of Gerontology and Geriatrics Pub Date : 2022-09-01 DOI:10.36150/2499-6564-n564

I. Mattioli, Francesca Remelli, M. Brunori, C. delli Gatti, A. Zurlo, S. Volpato

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引用次数: 0

摘要

我们提出一个病例87岁的妇女住院慢性水样腹泻，由多种疾病的影响。经生物体液和微生物检查排除其他腹泻原因后，行内镜检查，未见宏观异常，但在随机活检的组织学检查中，发现胶原性结肠炎的特征。停用患者长期服用的兰索拉唑和舍曲林，开始使用布地奈德，临床立即改善。胶原性结肠炎是一种罕见的高龄慢性腹泻的病因，但在接受多种药物治疗的患者中，应在准确的鉴别诊断后加以怀疑。

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A drug-induced microscopic colitis in an older woman: a case report

We presented a case of a 87-year-old woman hospitalized for chronic watery diarrhea, affected by multimorbidities. After excluding other causes of diarrhea by biohumoral and microbiological tests, endoscopy was performed without revealing any macroscopic abnormalities, but, at histological examination of random biopsies, the characteristic features of collagenous colitis were found. Lansoprazolo and sertraline, chronically taken by the patient, was discontinued, and budesonide was started with prompt clinical improvement. Collagenous colitis is a rare cause of chronic diarrhea in advanced age, but it should be suspected in patients with polypharmacotherapy, after an accurate differential diagnosis.

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来源期刊

Journal of Gerontology and Geriatrics GERONTOLOGY-

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： The Journal of Gerontology and Geriatrics (JGG) is the official journal of the Italian Society of Gerontology and Geriatrics (SIGG), which will be an international, interdisciplinary, peer-reviewed journal concerning frontiers and advances in the field of aging. The aim of the journal is to provide a forum for original research papers, reviews, clinical case reports, and commentaries on the most relevant areas pertaining to aging. JGG publishes relevant articles covering the full range of disciplines pertaining to aging. Appropriate areas include (but are not limited to) Physiology and Pathology of Aging, Biogerontology, Epidemiology, Clinical Geriatrics, Pharmacology, Ethics, Psychology, Sociology and Geriatric Nursing.