尼泊尔第二省癌症患者临床概况:单中心经验

Anshul Thakur, Anishee Shah, B. Ray
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摘要

简介癌症在尼泊尔的发病率正在上升。据估计,到2020年,男性的发病率将达到每100000人38.5人,女性的发病率为每100000人41.5人。确定尼泊尔省一级癌症负担的研究不够充分,已经进行的研究更倾向于第3省。通过在该地区建立专门的癌症设施,我们概述了2省癌症患者的临床情况。方法我们对2019年5月至2020年2月期间在肿瘤诊所注册的118名患者进行了单中心回顾性审查。从病历中获得人口统计学、诊断和治疗策略。结果癌症的中位发病年龄为55岁(6~83岁),最大发病年龄为50~60岁(31.4%),女性71例(60.2%),男性47例(39.8%)。常见的癌症有胃肠道癌(27.1%)、乳腺癌(16.9%)、头颈部癌(15.3)、妇科癌(13.6%)、血液学癌(11.9%)和其他癌(15.2%)。在胃肠道癌中,胆囊癌15例(46.9%)最常见,其次是癌症6例(18.8%)和癌症4例(12.5%),78名患者(66.1%)只接受姑息治疗,25名患者(21.2%)只接受化疗,8名患者(6.8%)只进行了手术,3名患者(2.5%)同时进行了手术和化疗,2名患者(1.7%)同时接受了化疗和姑息治疗,2名病人(1.7%)得到了安慰和观察。结论任何类型癌症最常见的发病年龄为50-60岁,最常见的癌症起源于胃肠道。大多数患者由于表现为晚期而接受姑息治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Overview of Cancer Patients in Province Two of Nepal: A Single Center Experience
Introduction The incidence of cancer is rising in Nepal. It is estimated to reach 38.5 per 100,000 for males and 41.5 per 100,000 for females by 2020. The studies to determine the cancer burden in Nepal at provincial level have been insufficient and those that have been done are more inclined to Province 3. With establishment of a dedicated cancer facility in this area, we present an overview of clinical scenario of cancer patients in Province 2.MethodsWe performed a single centered, retrospective review of 118 patients who were registered in Oncology Clinics between May 2019 and February 2020. Demographics, diagnoses and the treatment strategies were obtained from the medical records.ResultsMedian age of presentation for cancer was 55 years (range, 6 to 83 years) with maximum number of patients falling within range of 50-60 years (31.4%). 71 patients (60.2%) were female and 47 patients (39.8%) were male. The common presenting cancers were gastrointestinal (27.1%), breast (16.9%), head and neck (15.3), gynecological (13.6%), hematological (11.9%) and others (15.2%). Among the gastrointestinal cancers, carcinoma of gallbladder with 15 cases (46.9%) was the most frequently occurring, followed by colorectal cancer with 6 cases (18.8%) and esophageal cancer with 4 cases (12.5%). Among all, 78 patients (66.1%) received palliative care only, 25 patients (21.2%) received chemotherapy only, 8 patients (6.8%) underwent surgery only, 3 patients (2.5%) underwent surgery and received chemotherapy as well, 2 patients (1.7%) received both chemotherapy and palliative care and 2 patients (1.7%) were reassured and observed. ConclusionThe most common age of presentation for cancer of any type was 50-60 years, with most common cancer being gastrointestinal in origin. Most of the patients received palliative care owing to their advanced stage at presentation.
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