运动障碍脑铁磁共振成像研究进展

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY

Behavioural Neurology Pub Date : 2022-02-24 DOI:10.1155/2022/3972173

N. Tambasco, P. Nigro, A. Chiappiniello, F. Paolini Paoletti, Sara Scialpi, S. Simoni, P. Chiarini, L. Parnetti

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引用次数: 4

摘要

脑铁负荷是运动障碍最重要的神经病理标志之一。具体来说，铁提供了大脑中大部分顺磁性金属信号，它的积累似乎在基底神经节和其他大脑结构的退化中起着关键作用，尽管还没有完全解释清楚。此外，铁的分布模式与描述不同的运动障碍有关。本研究综述了目前关于脑铁检测和定量的磁共振成像(MRI-BIDQ)在运动障碍神经退行性过程中的研究。

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An Updated Overview of the Magnetic Resonance Imaging of Brain Iron in Movement Disorders

Brain iron load is one of the most important neuropathological hallmarks in movement disorders. Specifically, the iron provides most of the paramagnetic metal signals in the brain and its accumulation seems to play a key role, although not completely explained, in the degeneration of the basal ganglia, as well as other brain structures. Moreover, iron distribution patterns have been implicated in depicting different movement disorders. This work reviewed current literature on Magnetic Resonance Imaging for Brain Iron Detection and Quantification (MRI-BIDQ) in neurodegenerative processes underlying movement disorders.

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来源期刊

Behavioural Neurology 医学-临床神经学

CiteScore

5.40

自引率

3.60%

发文量

审稿时长

>12 weeks

期刊介绍： Behavioural Neurology is a peer-reviewed, Open Access journal which publishes original research articles, review articles and clinical studies based on various diseases and syndromes in behavioural neurology. The aim of the journal is to provide a platform for researchers and clinicians working in various fields of neurology including cognitive neuroscience, neuropsychology and neuropsychiatry. Topics of interest include: ADHD Aphasia Autism Alzheimer’s Disease Behavioural Disorders Dementia Epilepsy Multiple Sclerosis Parkinson’s Disease Psychosis Stroke Traumatic brain injury.