视网膜血氧测定的假彩色方法

Erwin Michel Davila-Iniesta, Santiago Guerrero-Gonzalez, Jorge Santiago-Amaya, Paola Castillo-Juárez, Luis Niño-de-Rivera-Oyarzabal
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引用次数: 0

摘要

血氧仪是测量血液中血红蛋白氧饱和度的一种方法。特别是基于视网膜血管血氧饱和度测量的视网膜血氧测定法,在收集视网膜内外血管的血氧信息方面获得了极大的兴趣。基于成像光谱学的无创分光光度法视网膜血氧测定已经研究了50多年。然而,光学相干断层扫描(OCT)是分析氧化血红蛋白(HbO2)和脱氧血红蛋白(Hb)在视网膜血管和脉络膜结构中的吸收差异的另一种选择。我们在本文中提出了一种替代方法来操作常规OCT图像来评估相对血红蛋白氧饱和度的变化。将570 nm和600 nm灰度的常规OCT图像转换为相应的色阶,与原始灰度OCT图像中涉及的氧合信息进行比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
False Color Method for Retinal Oximetry
Oximetry is a method for measuring the oxygen saturation of haemoglobin in blood. Particularly, retinal oximetry based in the measurement of oxygen saturation in retinal vessels has acquired great interest to gather information on blood oxygenation from said vessels within inner and outer retina. Non-invasive spectrophotometric retinal oximetry has been studied for over five decades based on imaging spectroscopy. However, Optical Coherence Tomography (OCT) is an alternative to analyze the absorption difference between oxyhaemoglobin (HbO2) and deoxyhaemoglobin (Hb) in the retinal vessels and the choroidal structure. We propose in this paper an alternative process to manipulate conventional OCT images to evaluate changes in the relative haemoglobin oxygen saturation. Conventional OCT images from 570 nm and 600 nm in gray scale are converted to a corresponding color scale to be compared to the oxygenation information involved in the original gray scale OCT images.
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