成年拉布拉多猎犬的转移性胃腺癌与肥厚性胃病相似

Q4 Veterinary
T. Sarandy, Carlos A Lopes, F. Del Piero, R. Ecco
{"title":"成年拉布拉多猎犬的转移性胃腺癌与肥厚性胃病相似","authors":"T. Sarandy, Carlos A Lopes, F. Del Piero, R. Ecco","doi":"10.24070/bjvp.1983-0246.v14i2p123-128","DOIUrl":null,"url":null,"abstract":"We describe a case of hypertrophic gastropathy (Ménétrier’s like disease) with metastatic gastric adenocarcinoma in a seven-year-old intact female Labrador Retriever dog. The animal suddenly presented with emesis and died. Gross lesions included a marked diffuse thickening of the gastric mucosa and an ulcerated transmural neoplastic mass in the gastric body. Gastric body and fundus were affected by foveolar hyperplasia with loss of chief and parietal cells replaced by mucous cells and marked dilatation of gastric glands. An area of gastric adenocarcinoma with submucosal lymphatic vessels invasion was also present and metastases were observed in the gastric lymph nodes, small intestine, pancreas, lung and liver. Due to its similarity with other gastric proliferative disorders, including this condition in the list of differentials is a necessary step in the diagnostic investigation of canine gastropathies.","PeriodicalId":9223,"journal":{"name":"Brazilian Journal of Veterinary Pathology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metastatic gastric adenocarcinoma associated with hypertrophic gastropathy resembling Ménétrier's disease in an adult Labrador Retriever dog\",\"authors\":\"T. Sarandy, Carlos A Lopes, F. Del Piero, R. Ecco\",\"doi\":\"10.24070/bjvp.1983-0246.v14i2p123-128\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We describe a case of hypertrophic gastropathy (Ménétrier’s like disease) with metastatic gastric adenocarcinoma in a seven-year-old intact female Labrador Retriever dog. The animal suddenly presented with emesis and died. Gross lesions included a marked diffuse thickening of the gastric mucosa and an ulcerated transmural neoplastic mass in the gastric body. Gastric body and fundus were affected by foveolar hyperplasia with loss of chief and parietal cells replaced by mucous cells and marked dilatation of gastric glands. An area of gastric adenocarcinoma with submucosal lymphatic vessels invasion was also present and metastases were observed in the gastric lymph nodes, small intestine, pancreas, lung and liver. Due to its similarity with other gastric proliferative disorders, including this condition in the list of differentials is a necessary step in the diagnostic investigation of canine gastropathies.\",\"PeriodicalId\":9223,\"journal\":{\"name\":\"Brazilian Journal of Veterinary Pathology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brazilian Journal of Veterinary Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24070/bjvp.1983-0246.v14i2p123-128\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Veterinary\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Journal of Veterinary Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24070/bjvp.1983-0246.v14i2p123-128","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Veterinary","Score":null,"Total":0}
引用次数: 0

摘要

我们描述了一例肥大性胃病(Ménétrier样疾病)伴转移性胃腺癌的病例,发生在一只7岁的完整雌性拉布拉多寻回犬身上。这只动物突然呕吐而死。大体病变包括胃粘膜明显弥漫性增厚和胃体溃疡性透壁肿瘤块。胃体和胃底受到小凹增生的影响,主要细胞和顶叶细胞的损失被粘液细胞取代,胃腺明显扩张。胃腺癌也有粘膜下淋巴管浸润的区域,并在胃淋巴结、小肠、胰腺、肺和肝中观察到转移。由于其与其他胃增殖性疾病相似,将这种情况列入差异列表是犬胃病诊断研究的必要步骤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Metastatic gastric adenocarcinoma associated with hypertrophic gastropathy resembling Ménétrier's disease in an adult Labrador Retriever dog
We describe a case of hypertrophic gastropathy (Ménétrier’s like disease) with metastatic gastric adenocarcinoma in a seven-year-old intact female Labrador Retriever dog. The animal suddenly presented with emesis and died. Gross lesions included a marked diffuse thickening of the gastric mucosa and an ulcerated transmural neoplastic mass in the gastric body. Gastric body and fundus were affected by foveolar hyperplasia with loss of chief and parietal cells replaced by mucous cells and marked dilatation of gastric glands. An area of gastric adenocarcinoma with submucosal lymphatic vessels invasion was also present and metastases were observed in the gastric lymph nodes, small intestine, pancreas, lung and liver. Due to its similarity with other gastric proliferative disorders, including this condition in the list of differentials is a necessary step in the diagnostic investigation of canine gastropathies.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Brazilian Journal of Veterinary Pathology
Brazilian Journal of Veterinary Pathology Veterinary-Veterinary (miscellaneous)
CiteScore
0.60
自引率
0.00%
发文量
24
期刊介绍: The Brazilian Journal of Veterinary Pathology is the official electronic periodical of the Brazilian Association of Veterinary Pathology. The purpose of the BJVP is to publish original full papers, short communications, case reports, letters, reviews (by invited experts) and abstracts of scientific meetings. The preferable subjects is natural and experimental pathology. All the articles are submitted to scientific reviewers.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信