心血管风险与认知衰老相关的队列差异

IF 0.8 Q4 PSYCHOLOGY, DEVELOPMENTAL

GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry Pub Date : 2018-11-21 DOI:10.1024/1662-9647/a000198

P. Karlsson, B. Johansson, I. Skoog, J. Skoog, L. Rydén, Valgeir Thorvaldsson

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引用次数: 2

摘要

目的：研究70岁至79岁之间心血管风险和液体认知之间的出生队列差异。方法：数据来自1901年-1902年、1906年-1907年和1930年出生的代表性人群队列样本（H70），在70岁、75岁和79岁时测量流体认知测量（空间能力和逻辑推理）。Framingham风险评分（FRS）来源于基于办公室的非流产预测因素（年龄、性别、收缩压、BMI、吸烟、糖尿病状况），用于测量心血管风险。数据拟合了多组潜在生长曲线模型。研究结果：估计显示FRS和流体认知之间有很小的关联。这些关联在1930年的队列中略有减少。结论：研究结果表明，在出生较晚的队列中，心血管风险对认知衰老的不良影响正在减少。

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Cohort Differences in the Association of Cardiovascular Risk and Cognitive Aging

Aim: To investigate birth cohort differences in associations between cardiovascular risk and fluid cognition between the age of 70 and 79. Method: Data were drawn from representative population-based cohort samples (H70), born 1901–1902, 1906–1907, and 1930, measured at ages 70, 75, and 79 on fluid cognitive measures (spatial ability and logical reasoning). The Framingham Risk Score (FRS), derived from office-based nonlaboratory predictors (age, sex, systolic blood pressure, BMI, smoking, diabetes status), was used to measure cardiovascular risk. Multiple-group latent growth curve models were fitted to the data. Findings: Estimates revealed small associations between the FRS and fluid cognition. These associations were slightly reduced in the 1930 cohort. Conclusion: Findings suggest diminishing adverse effects of cardiovascular risk on cognitive aging in cohorts born later.

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来源期刊

GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry PSYCHOLOGY, DEVELOPMENTAL-

CiteScore

2.00

自引率

0.00%

发文量