钙调磷酸酶抑制剂在角膜移植中的应用

Pub Date : 2017-09-01 DOI:10.12816/0047760

A. Alamri

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引用次数: 0

摘要

圆锥角膜是一种非炎性扩张性疾病。圆锥角膜的患病率因地区、人群、种族、环境因素和诊断标准而异1,2。穿透性角膜移植(PK)是最常见的角膜移植手术。大约20%的正常风险角膜移植会出现急性排斥反应。圆锥角膜的治疗因病情严重而异。局部类固醇在预防PK5后观察到的免疫反应方面是有效的。

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Calcineurin Inhibitor in Corneal Transplantation

165 Keratoconus is a non-inflammatory ectatic disease. The prevalence of keratoconus varies with location, population, ethnicity, environmental factors and diagnostic criteria1,2. Penetrating keratoplasty (PK) is the most common type of corneal transplant3. Approximately 20% of normal-risk corneal transplants experience an episode of acute rejection4. Management of keratoconus varies with disease severity. Topical steroids are effective in the prophylaxis against immune reactions observed after PK5.

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