Mikroekstrakcija čvrstom fazom – inovativni pristup u bioanalitičkim istraživanjima

In last three decades, the solid-phase microextraction technology has brought significant progress in bioanalytical research due to the versatility of this fast and solvent-free approach to biological sample preparation. It has been widely used in combination with various analytical instrumenta - tion, even if most of the work has been done by coupling the extraction technique with liquid or gas chromatography. This review focuses on the new developments and advances in solid-phase microextraction-based techniques. Furthermore, some interesting, new innovations that fail to go beyond academic research are also reported.