2天抗生素疗程是否能降低心脏骤停后接受定向体温管理的患者呼吸机相关性肺炎的发生率?

Q4 Medicine

Clinical Pulmonary Medicine Pub Date : 2020-03-01 DOI:10.1097/CPM.0000000000000352

E. Lafond, D. Zappetti

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引用次数: 0

摘要

摘要:这项双盲、随机对照试验评估了阿莫西林-克拉维酸2天疗程在降低院外心脏骤停伴有初始震荡节律后接受靶向温度管理的患者早期呼吸机相关肺炎发生率方面的疗效。与安慰剂相比，治疗组早期呼吸机相关肺炎的发生率显著降低，但无呼吸机天数和第28天死亡率没有减少。资料来源:Francois B, Cariou A, Clere-Jehl R等。心脏骤停后早期呼吸机相关性肺炎的预防。中华检验医学杂志，2019;31(1):331 - 342。

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Does a 2-Day Course of Antibiotics Lower the Incidence of Ventilator-associated Pneumonia in Patients Undergoing Targeted Temperature Management Following Cardiac Arrest?

Synopsis: This double-blind, randomized control trial evaluated the efficacy of a 2-day course of amoxicillin-clavulanate in reducing the incidence of early ventilator-associated pneumonia in patients undergoing targeted temperature management following an out-of-hospital cardiac arrest with initial shockable rhythm. There was a significant reduction in the incidence of early ventilator-associated pneumonia in the treatment group when compared with placebo, but no reduction in ventilator-free days or mortality at day 28. Source: Francois B, Cariou A, Clere-Jehl R, et al. Prevention of early ventilator-associated pneumonia after cardiac arrest. N Engl J Med. 2019;381:1831–1842.

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来源期刊

Clinical Pulmonary Medicine Medicine-Critical Care and Intensive Care Medicine

自引率

0.00%

发文量

期刊介绍： Clinical Pulmonary Medicine provides a forum for the discussion of important new knowledge in the field of pulmonary medicine that is of interest and relevance to the practitioner. This goal is achieved through mini-reviews on focused sub-specialty topics in areas covered within the journal. These areas include: Obstructive Airways Disease; Respiratory Infections; Interstitial, Inflammatory, and Occupational Diseases; Clinical Practice Management; Critical Care/Respiratory Care; Colleagues in Respiratory Medicine; and Topics in Respiratory Medicine.